https://scholars.lib.ntu.edu.tw/handle/123456789/45895
標題: | New Nardosinanes and 19-Oxygenated Ergosterols from the Soft Coral Nephthea armata Collected in Taiwan | 作者: | El-Gamal, Ali A. H. Wang, Shang-Kwei Dai, Chang-Feng Duh, Chang-Yih |
公開日期: | 2004 | 卷: | 67 | 期: | 9 | 起(迄)頁: | 1455-1458 | 來源出版物: | Journal of Natural Products | 摘要: | Five new nardosinane sesquiterpenoids, armatins A-E (1-5), lemnal-1(10)-ene-2,12-dione (6) (a new natural product), and two new cytotoxic 19-oxygenated ergosterols, armatinols A and B (7 and 8), were isolated from the methylene chloride extract of the soft coral Nephthea armata, collected in Taiwan. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity was determined against selected cancer cells. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-4644371070&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/307993 http://ntur.lib.ntu.edu.tw/bitstream/246246/174367/1/38.pdf |
DOI: | 10.1021/np0400858 | SDG/關鍵字: | armatin a; armatin b; armatin c; armatin d; armatin e; armatinol a; armatinol b; ergosterol; lemnal 1(10) ene 2,12 dione; nardosinane derivative; sesquiterpenoid; unclassified drug; antineoplastic activity; article; carbon nuclear magnetic resonance; cell strain HT29; coelenterate; drug isolation; drug structure; human; human cell; Nephthea armata; nuclear Overhauser effect; proton nuclear magnetic resonance; Taiwan; Animals; Anthozoa; Antineoplastic Agents; Drug Screening Assays, Antitumor; Ergosterol; Humans; Leukemia P388; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Sesquiterpenes; Stereoisomerism; Taiwan; Tumor Cells, Cultured; Alcyonacea; Anthozoa; Coelenterata |
顯示於: | 海洋研究所 |
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