https://scholars.lib.ntu.edu.tw/handle/123456789/45960
標題: | Metabolites with Cytotoxic Activity from the Formosan Soft Coral Cladiella australis | 作者: | CHANG-FENG DAI | 關鍵字: | 3′-O-acetylthymidine; 5′-O-acetylthymidine; Cladiella australis; Cytotoxicity; p-Vinylbenzyl alcohol; Soft coral; Steroids | 公開日期: | 2006 | 卷: | 53 | 期: | 2 | 起(迄)頁: | 489-494 | 來源出版物: | Journal of the Chinese Chemical Society | 摘要: | The metabolites, (24S)-3β-acetoxyergost-5-en-21-oic acid (2), 5′-O-acetylthymidine (3), 3′-O-acetylthymidine (4), and p-vinylbenzyl alcohol (5), along with a known steroid (1) were isolated from the EtOAc extract of the Formosan soft coral Caldiella australis. The structures of new metabolites were determined on the basis of spectroscopic (including 1D and 2D NMR) analyses and by comparison of their NMR spectral data with those of related compounds. Except for 3, all compounds exhibited cytotoxic activity of various degrees of potency against a limited panel of human liver and breast cancer cell lines. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-34047094353&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/322446 http://ntur.lib.ntu.edu.tw/bitstream/246246/174436/1/57.pdf |
DOI: | 10.1002/jccs.200600064 |
顯示於: | 海洋研究所 |
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