https://scholars.lib.ntu.edu.tw/handle/123456789/46005
Title: | Novel Norhumulene and Xeniaphyllane-Derived Terpenoids from a Formosan Soft Coral Sinularia gibberosa | Authors: | Chen, Shin-Pin Su, Jui-Hsin Yeh, Hsiao-Chien Ahmed, Atallah Fouad CHANG-FENG DAI Wu, Yang-Chang Sheu, Jyh-Horng |
Keywords: | Cytotoxic; Diterpenoid; Sinularia gibberosa; Xeniaphyllane | Issue Date: | 2009 | Journal Volume: | 57 | Journal Issue: | 2 | Start page/Pages: | 162-166 | Source: | Chemical and Pharmaceutical Bulletin | Abstract: | A novel skeletal norhumulene (1) and six xeniaphyllane-derived compounds, including norditerpenoids (2, 3) and diterpenoids (4-7), were isolated from the EtOAc extract of the Formosan soft coral Sinularia gibberosa. Their structures were elucidated by spectroscopic analysis. In vitro cytotoxic evaluation of the above metabolites revealed that 2 and 4 showed weak cytotoxicity toward a few cancer cell lines. ? 2009 Pharmaceutical Society of Japan. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-61449187487&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/348445 http://ntur.lib.ntu.edu.tw/bitstream/246246/174482/1/99.pdf |
DOI: | 10.1248/cpb.57.162 | SDG/Keyword: | gibberosin n; gibberosin o; gibberosin p; gibberosin q; gibberosin r; gibberosin s; norhumulene; sinugibberoside f; terpenoid derivative; unclassified drug; xeniaphyllane derivative; article; coral; drug cytotoxicity; drug isolation; drug structure; human; human cell; Sinularia gibberosa; structure analysis; Animals; Anthozoa; Antineoplastic Agents; Cell Line, Tumor; Diterpenes; Drug Screening Assays, Antitumor; Magnetic Resonance Spectroscopy; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Taiwan; Terpenes; Tetrazolium Salts; Thiazoles |
Appears in Collections: | 海洋研究所 |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.