https://scholars.lib.ntu.edu.tw/handle/123456789/460867
Title: | Clinical implication for endometriosis associated with ovarian cancer | Authors: | PAO-LING TORNG | Issue Date: | 2017 | Journal Volume: | 6 | Journal Issue: | 4 | Start page/Pages: | 152-156 | Source: | Gynecology and Minimally Invasive Therapy | Abstract: | We reviewed current literature regarding the association of endometriosis and epithelial ovarian cancer based on epidemiology studies, molecular researches and clinical observations. Our methods include a review of literature research of MEDLINE, PubMed, Cochrane Library of Systematic Reviews and reference search in selected papers. The life time risk of epithelial ovarian cancer in women with endometriosis is low, yet there might be a cluster of individuals who have higher risk of developing epithelial ovarian cancer from endometriosis. Endometriosis associated ovarian cancer (EAOC) is predominant in particular histological subtypes of epithelial ovarian carcinoma and are related to some specific molecular aberrations. Clinical observations showed age as an important variable to the development of EAOC. Rapid growth of tumor and solid components in sonography are key features to detect malignant transformation of endometriosis. Evidence is not clear about prophylactic oophorectomy in preventing EAOC in patients with endometriosis. This review provided rationale data for identifying, monitoring, counseling and management of women with endometriosis who are potentially high risk for malignant transformation. ? 2017 |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/460867 | ISSN: | 2213-3070 | DOI: | 10.1016/j.gmit.2017.08.003 | SDG/Keyword: | age; cancer diagnosis; cancer risk; cancer survival; clinical observation; clinical outcome; disease association; echography; endometriosis; histology; human; malignant transformation; nonhuman; ovariectomy; ovary cancer; prevalence; priority journal; Review; risk factor; tumor growth |
Appears in Collections: | 醫學系 |
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