https://scholars.lib.ntu.edu.tw/handle/123456789/463652
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Cheng Y.-W | en_US |
dc.contributor.author | CHIN-HSIEN LIN | en_US |
dc.contributor.author | RUEY-MEEI WU | en_US |
dc.creator | RUEY-MEEI WU;Lin C.-H;Cheng Y.-W | - |
dc.date.accessioned | 2020-02-25T08:01:24Z | - |
dc.date.available | 2020-02-25T08:01:24Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1823-6138 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/463652 | - |
dc.description.abstract | Human immunodeficiency virus (HIV) infection can cause variable movement disorders, including parkinsonism. HIV-related parkinsonism usually responds well to highly-active antiretroviral therapy (HAART), suggesting a possible reversible dysfunction of the dopaminergic system. We report the case of a 42-year-old man who presented with rapidly progressive symmetric parkinsonism, cognitive decline, and loss of postural reflex as the initial manifestation of HIV infection. A significant improvement of his parkinsonism after HAART demonstrates a potentially reversible dopaminergic system dysfunction secondary to HIV infection. A normal 99mTc-TRODAT-1 SPECT image after HAART treatment paralleled the clinical improvement in extrapyramidal symptoms. Early identification of HIV-related parkinsonism, especially in patients with symmetrical akinetic-rigidity and early loss of posture reflex, is important for its potential reversibility with HAART therapy. | en_US |
dc.relation.ispartof | Neurology Asia | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | antiretrovirus agent; immunoglobulin G; lamivudine; nevirapine; zidovudine; adult; article; case report; CD4 lymphocyte count; clinical feature; cognitive defect; disease association; heterosexuality; human; Human immunodeficiency virus infection; hyperreflexia; immunoglobulin production; male; mental health; Mini Mental State Examination; neurologic examination; nuclear magnetic resonance imaging; parkinsonism; protein cerebrospinal fluid level; treatment duration; Unified Parkinson Disease Rating Scale; unsteadiness; virus load; white matter lesion | - |
dc.title | HIV-associated parkinsonism reversed with antiretroviral therapy | en_US |
dc.type | journal article | en |
dc.identifier.scopus | 2-s2.0-84904282335 | - |
dc.relation.pages | 199-203 | en_US |
dc.relation.journalvolume | 19 | en_US |
dc.relation.journalissue | 2 | en_US |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Neurology-NTUH | - |
crisitem.author.dept | Neurology | - |
crisitem.author.dept | The Clinical Center for Neuroscience and Behavior | - |
crisitem.author.dept | Neurology-NTUH | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.dept | Neurology | - |
crisitem.author.dept | The Clinical Center for Neuroscience and Behavior | - |
crisitem.author.dept | Psychology | - |
crisitem.author.orcid | 0000-0001-8566-7573 | - |
crisitem.author.orcid | 0000-0002-4947-5467 | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Science | - |
顯示於: | 醫學系 |
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