https://scholars.lib.ntu.edu.tw/handle/123456789/465264
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Huang Y.H. | en_US |
dc.contributor.author | Tseng S.P. | en_US |
dc.contributor.author | Hu J.M. | en_US |
dc.contributor.author | JUI-CHANG TSAI | en_US |
dc.contributor.author | PO-REN HSUEH | en_US |
dc.contributor.author | LEE-JENE TENG | en_US |
dc.creator | Huang Y.H.;Tseng S.P.;Hu J.M.;Jui-Chang Tsai;Hsueh P.R.;Teng L.J. | - |
dc.date.accessioned | 2020-02-27T03:47:00Z | - |
dc.date.available | 2020-02-27T03:47:00Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 1198-743X | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-34250319756&doi=10.1111%2fj.1469-0691.2007.01718.x&partnerID=40&md5=5a5e33f983b1d4c2422d10f9b42f55f6 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/465264 | - |
dc.description.abstract | The staphylococcal chromosome cassette (SCC) mec types of 382 hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA) isolates in Taiwan were analysed over a 7-year period (1999-2005). There was an abrupt increase in SCC mec type IV in HA-MRSA during 2005. The molecular epidemiology of a subset (n = 69) of HA-MRSA isolates with SCC mec types III, IV or V was characterised and compared with that of community-acquired MRSA (CA-MRSA) (n = 26, collected during 2005). Pulsed-field gel electrophoresis revealed three major pulsotypes (A, B and C) and 15 minor clones. Pulsotypes B and C, which contained isolates carrying SCC mec types IV and V, respectively, included both CA-MRSA and HA-MRSA isolates. Among 24 toxin genes analysed, five genes had significant differential distribution between CA-MRSA and SCC mec type III HA-MRSA. Furthermore, among SCC mec type IV isolates, the seb gene was detected more commonly in HA-MRSA. Analysis of representative members of the three major pulsotypes by multilocus sequence typing revealed two sequence types (STs), namely ST239 (SCC mec III) and ST59 (SCC mec IV or SCC mec V). This suggests that ST59:SCC mec IV, which is usually community-acquired, has become an important nosocomial pathogen in the hospital studied. ? 2007 The Authors; Journal compilation ? 2007 Blackwell Publishing Ltd. | - |
dc.publisher | Blackwell Publishing Ltd | - |
dc.relation.ispartof | Clinical Microbiology and Infection | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | bacterial protein; ciprofloxacin; clindamycin; cotrimoxazole; erythromycin; gene product; gentamicin; hemolysin; leukocidin; minocycline; oxacillin; protein mec; protein seb; rifampicin; Staphylococcus toxin; unclassified drug; vancomycin; adult; antibiotic sensitivity; article; bacterial chromosome; bacterial gene; bacterial genetics; bacterial growth; bacterial strain; bacterial transmission; bacterial virulence; bacterium detection; bacterium identification; bacterium isolate; child; clonal species; communicable disease; controlled study; female; gene cassette; hospital infection; human; major clinical study; male; methicillin resistant Staphylococcus aureus; molecular epidemiology; multilocus sequence typing; nonhuman; priority journal; pulsed field gel electrophoresis; strain difference; Taiwan; methicillin resistant Staphylococcus aureus | - |
dc.title | Clonal spread of SCCmec type IV methicillin-resistant Staphylococcus aureus between community and hospital | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1111/j.1469-0691.2007.01718.x | - |
dc.identifier.pmid | 17403129 | - |
dc.identifier.scopus | 2-s2.0-34250319756 | - |
dc.relation.pages | 717-724 | - |
dc.relation.journalvolume | 13 | - |
dc.relation.journalissue | 7 | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Laboratory Medicine-NTUH | - |
crisitem.author.dept | Clinical Laboratory Sciences and Medical Biotechnology | - |
crisitem.author.orcid | 0000-0003-2723-6841 | - |
crisitem.author.orcid | 0000-0002-7502-9225 | - |
crisitem.author.orcid | 0000-0003-0104-741X | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫學系 |
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