https://scholars.lib.ntu.edu.tw/handle/123456789/465842
Title: | ABO blood groups in peptic ulcer disease | Authors: | MING-JIUM SHIEH Wang C.-Y. Wong J.-M. |
Keywords: | ABO blood group; Peptic ulcer disease | Issue Date: | 1998 | Publisher: | Center for Biomedical Engineering, NTU College of Medicine, Taipei, Taiwan | Journal Volume: | 10 | Journal Issue: | 1 | Start page/Pages: | 49-52 | Source: | Biomedical Engineering - Applications, Basis and Communications | Abstract: | A prospective study using primary panendoscopy with two aims at the National Taiwan University Hospital (NTLH) was conducted. To provide a possible opportunity to determine the prevalence on peptic ulcer diseases (PUD) and to evaluate the association between the ABO blood group and PUD in general populations. During one year period, 2987 patients (1854 males and 1133 females) admitted for physical checkup were enrolled for study. The patients ranged from 20 to 81 years of age. The mean age was 52 yr for males and 51 yr for females. There were 24% of males and 16% of females diagnosed to have PUD endoscopically yielding a 21% prevalence rate overall. The cases of duodenal ulcer were approximately three times those of gastric ulcer in each sex (17% VS 6%) PUD were apparently more apt to occur in males than in females in each ABO blood group (p < 0.05) the difference of the prevalence rate of PUD between various blood groups was not significant in males. On the other hand, females of blood O group showed the highest prevalence rate of PUD compared with those of the other blood groups (p < 0.05). When the location of ulcers was used to classified patients into two subgroups the tendency of male predominance remained true in both subgroups (P < 0.05). But the preponderance of blood group O among peptic ulcer subjects was only observed in females with duodenal ulcer in gastric ulcer, however, the prevalence rate among various ABO blood groups was similar in each sex. In conclusion, the prevalence rate of PUD in general populations was 21% in Taiwan, and the preponderance of blood group O among peptic ulcer subjects was only observed in females with duodenal ulcer.A prospective study using primary panendoscopy with two aims at the National Taiwan University Hospital (NTUH) was conducted, to provide a possible opportunity to determine the prevalence on peptic ulcer diseases (PUD) and to evaluate the association between the ABO blood group and PUD in general populations. During one year period 2987 patients (1854 males and 1133 females) admitted for physical checkup were enrolled for study. The patients ranged from 20 to 81 years of age. The mean age was 52 yr. for males and 51 yr. for females. There were 24% of males and 16% of females diagnosed to have PUD endoscopically, yielding a 21% prevalence rate overall. The cases of duodenal ulcer were approximately three times those of gastric ulcer in each sex (17% VS 6%). PUD were apparently more apt to occur in males than in females in each ABO blood group (p<0.05), the difference of the prevalence rate of PUD between various blood groups was not significant in males. On the other hand, females of blood O group showed the highest prevalence rate of PUD, compared with those of the other blood groups (p<0.05). When the location of ulcers was used to classified patients into two subgroups, the tendency of male predominance remained true in both subgroups (P<0.05). But the preponderance of blood group O among peptic ulcer subjects was only observed in females with duodenal ulcer. In gastric ulcer, however, the prevalence rate among various ABO blood groups was similar in each sex. In conclusion, the prevalence rate of PUD in general populations was 21% in Taiwan, and the preponderance of blood group O among peptic ulcer subjects was only observed in females with duodenal ulcer. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032564890&partnerID=40&md5=5a12eca2616c297d4e2359bd9dbcae9e https://scholars.lib.ntu.edu.tw/handle/123456789/465842 |
ISSN: | 1016-2372 | SDG/Keyword: | Blood; Diseases; Patient treatment; Physiology; ABO blood groups; Peptic ulcer disease; Diagnosis; adult; aged; article; blood group; blood group ABO system; controlled study; duodenum ulcer; female; human; major clinical study; male; risk assessment; risk factor; stomach ulcer |
Appears in Collections: | 醫學工程學研究所 |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.