https://scholars.lib.ntu.edu.tw/handle/123456789/466029
標題: | Gastric cancer in the young | 作者: | I-RUE LAI WEN-JENG LEE CHIUNG-NIEN CHEN PO-HUANG LEE KING-JEN CHANG Chang-Yu S. Chen K.-M. |
公開日期: | 1997 | 卷: | 44 | 期: | 18 | 起(迄)頁: | 1641-1645 | 來源出版物: | Hepato-Gastroenterology | 摘要: | Background/Aims: Gastric cancer in the young is relatively uncommon, but it carries important clinical significance. This study was designed to determine the clinicopathological characteristics of young patients who underwent a gastrectomy for gastric cancer in order to improve clinical management. Methodology: From January 1977 to December 1994, 997 patients underwent surgical treatment for gastric cancer in the Department of Surgery of the National Taiwan University Hospital. All of these patients were classified into 6 groups based on their age at the time of surgery. Of these, 52 patients (5.2%) were 35 years of age or younger. The clinicopathological data of these patients were reviewed and compared to the data of the other age groups. Results: There was a female predominance, with a male:female ratio of 1:1.36. In the majority of patients, the time period from the onset of symptoms to the time of diagnosis was less than one year (76.9%). Epigastralgia was the most common complaint (65.4%). Six patients (11%) were diagnosed as having a benign peptic ulcer during the first endoscopy. Histologically, there were more diffuse (65.4%) and scirrhous types of gastric cancer in the young group. Half of the patients (49.9%) were at TNM stage III or IV at the time of surgery. Curative resections were performed on 49 patients. The cumulative 5-year survival rate was 36.1% among the young patients, which was no different from the survival rates of the other age groups. While the 5-year survival rate of patients with stage I gastric cancer was 90% in the young age group, of the 26 patients with stage III or IV, only one survived more than 5 years. Four female patients (13.3%) were found to have metastases to the ovaries during follow-up. Conclusion: The clinicopathological characteristics of young patients with gastric cancer are as follows: 1) female dominance; 2) more diffuse and scirrhous types of gastric carcinoma; 3) the prognosis after surgery depends on the stage rather than the age; 4) free use of endoscopy and clinical alertness are important for the early diagnosis of malignancy in young patients. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030819768&partnerID=40&md5=aa570ba6cac0fa83752ca49a5cdcfe26 https://scholars.lib.ntu.edu.tw/handle/123456789/466029 |
ISSN: | 0172-6390 | SDG/關鍵字: | adult; article; cancer staging; cancer survival; clinical feature; early diagnosis; endoscopy; epigastric pain; female; follow up; gastrectomy; human; major clinical study; male; ovary metastasis; pathology; patient care; peptic ulcer; priority journal; prognosis; sex ratio; stomach cancer; symptom; Adult; Aged; Female; Follow-Up Studies; Humans; Male; Middle Aged; Retrospective Studies; Sex Distribution; Stomach Neoplasms; Survival Rate |
顯示於: | 解剖學暨細胞生物學科所 |
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