https://scholars.lib.ntu.edu.tw/handle/123456789/468740
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Yu R. | en_US |
dc.contributor.author | MING-HSIEN HSIEH | en_US |
dc.contributor.author | Wang H.-L.S. | en_US |
dc.contributor.author | CHIH-MIN LIU | en_US |
dc.contributor.author | CHEN-CHUNG LIU | en_US |
dc.contributor.author | TZUNG-JENG HWANG | en_US |
dc.contributor.author | YI-LING CHIEN | en_US |
dc.contributor.author | Hwu H.-G. | en_US |
dc.contributor.author | WEN-YIH TSENG | en_US |
dc.creator | WEN-YIH TSENG;Hwu H.-G.;Chien Y.-L.;Hwang T.-J.;Liu C.-C.;Liu C.-M.;Wang H.-L.S.;Hsieh M.H.;Yu R. | - |
dc.date.accessioned | 2020-03-03T03:06:38Z | - |
dc.date.available | 2020-03-03T03:06:38Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84874593561&doi=10.1371%2fjournal.pone.0057516&partnerID=40&md5=9e78248519308c4ce1d0f4f598734683 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/468740 | - |
dc.description.abstract | Low frequency oscillations are essential in cognitive function impairment in schizophrenia. While functional connectivity can reveal the synchronization between distant brain regions, the regional abnormalities in task-independent baseline brain activity are less clear, especially in specific frequency bands. Here, we used a regional homogeneity (ReHo) method combined with resting-state functional magnetic resonance imaging to investigate low frequency spontaneous neural activity in the three different frequency bands (slow-5:0.01-0.027 Hz; slow-4:0.027-0.08 Hz; and typical band: 0.01-0.08 Hz) in 69 patients with schizophrenia and 62 healthy controls. Compared with controls, schizophrenia patients exhibited decreased ReHo in the precentral gyrus, middle occipital gyrus, and posterior insula, whereas increased ReHo in the medial prefrontal cortex and anterior insula. Significant differences in ReHo between the two bands were found in fusiform gyrus and superior frontal gyrus (slow-4> slow-5), and in basal ganglia, parahippocampus, and dorsal middle prefrontal gyrus (slow-5> slow-4). Importantly, we identified significant interaction between frequency bands and groups in the inferior occipital gyrus and caudate body. This study demonstrates that ReHo changes in schizophrenia are widespread and frequency dependent. ? 2013 Yu et al. | - |
dc.relation.ispartof | PLoS ONE | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; anterior insula; article; basal ganglion; brain region; controlled study; electroencephalogram; female; fusiform gyrus; human; major clinical study; male; middle frontal gyrus; nerve cell; occipital gyrus; parahippocampal gyrus; posterior insula; prefrontal cortex; primary motor cortex; schizophrenia; sensorimotor function; superior frontal gyrus; Adult; Brain; Brain Mapping; Case-Control Studies; Demography; Female; Humans; Male; Schizophrenia | - |
dc.title | Frequency Dependent Alterations in Regional Homogeneity of Baseline Brain Activity in Schizophrenia | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1371/journal.pone.0057516 | - |
dc.identifier.pmid | 23483911 | - |
dc.identifier.scopus | 2-s2.0-84874593561 | - |
dc.relation.journalvolume | 8 | - |
dc.relation.journalissue | 3 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.dept | Neurobiology and Cognitive Science Center | - |
crisitem.author.dept | Center for Integrated Dementia Care | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Center for Artificial Intelligence and Advanced Robotics | - |
crisitem.author.dept | Medical Device and Imaging | - |
crisitem.author.dept | Biomedical Engineering | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.dept | Medical Imaging-NTUH | - |
crisitem.author.orcid | 0000-0002-3585-7843 | - |
crisitem.author.orcid | 0000-0001-7016-8990 | - |
crisitem.author.orcid | 0000-0002-9290-110X | - |
crisitem.author.orcid | 0000-0001-7894-9484 | - |
crisitem.author.orcid | 0000-0002-3477-3015 | - |
crisitem.author.orcid | 0000-0002-2314-6868 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | Others: University-Level Research Centers | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | Others: University-Level Research Centers | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Engineering | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫療器材與醫學影像研究所 |
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