https://scholars.lib.ntu.edu.tw/handle/123456789/470195
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | SUNG-HSIN KUO | en_US |
dc.contributor.author | HUANG-CHUN LIEN | en_US |
dc.contributor.author | You S.-L. | en_US |
dc.contributor.author | YEN-SHEN LU | en_US |
dc.contributor.author | CHING-HUNG LIN | en_US |
dc.contributor.author | Chen T.-Z. | en_US |
dc.contributor.author | CHIUN-SHENG HUANG | en_US |
dc.creator | Kuo S.-H.;Huang-Chun Lien;You S.-L.;Lu Y.-S.;Lin C.-H.;Chen T.-Z.;Huang C.-S. | - |
dc.date.accessioned | 2020-03-05T05:51:22Z | - |
dc.date.available | 2020-03-05T05:51:22Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0960-9776 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-56749167950&doi=10.1016%2fj.breast.2008.05.006&partnerID=40&md5=90d336f6c3b550c013646c7f2fb24860 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/470195 | - |
dc.description.abstract | To assess the effect of a non-standard dose and regimen of adjuvant chemotherapy on the clinical outcome in stage I-II and operable stage III Taiwanese breast cancer patients. Variables studied included treatment variation (regimen and dose of adjuvant therapy), lymph node status, tumor size, histologic grade, and hormone receptor status. Cox's multivariate regression analyses were used to select prognostic factors significant for disease-free survival (DFS) and overall survival (OS). In the multivariate analysis, lymph node-positive, a tumor size greater than 5 cm, grade III, hormone receptor-negative status, and non-standard adjuvant chemotherapy were independent prognostic factors for DFS and/or OS. Node-positive patients treated with standard adjuvant chemotherapy had a significantly better DFS (HR = 0.6; P = 0.032) and OS (HR = 0.54; P = 0.025) than those treated with non-standard adjuvant chemotherapy. Breast cancer patients receiving standard adjuvant chemotherapy have a better DFS and OS than those receiving non-standard adjuvant chemotherapy. ? 2008 Elsevier Ltd. All rights reserved. | - |
dc.publisher | Churchill Livingstone | - |
dc.relation.ispartof | Breast | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | anthracycline derivative; antineoplastic agent; carboplatin; cisplatin; cyclophosphamide; doxorubicin; epirubicin; fluorouracil; hormone receptor; methotrexate; paclitaxel; recombinant granulocyte colony stimulating factor; thiotepa; adult; aged; article; breast cancer; breast carcinoma; cancer adjuvant therapy; cancer combination chemotherapy; cancer grading; cancer patient; cancer staging; cancer survival; controlled study; disease free survival; drug megadose; female; human; lymph node metastasis; major clinical study; multiple cycle treatment; optimal drug dose; overall survival; peripheral blood stem cell transplantation; priority journal; prognosis; repeated drug dose; stem cell mobilization; Taiwan; treatment outcome; tumor volume | - |
dc.title | Dose variation and regimen modification of adjuvant chemotherapy in daily practice affect survival of stage I-II and operable stage III Taiwanese breast cancer patients | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.breast.2008.05.006 | - |
dc.identifier.pmid | 18595699 | - |
dc.identifier.scopus | 2-s2.0-56749167950 | - |
dc.relation.pages | 646-653 | - |
dc.relation.journalvolume | 17 | - |
dc.relation.journalissue | 6 | - |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
crisitem.author.dept | Oncology | - |
crisitem.author.dept | Radiation Oncology-NTUCC | - |
crisitem.author.dept | Division of Radiation Oncology | - |
crisitem.author.dept | Pathology | - |
crisitem.author.dept | Pathology-NTUH | - |
crisitem.author.dept | Oncology-NTUH | - |
crisitem.author.dept | Clinical Trial Center | - |
crisitem.author.dept | Oncology | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Medical Oncology-NTUCC | - |
crisitem.author.dept | Oncology-NTUH | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.orcid | 0000-0003-0054-887X | - |
crisitem.author.orcid | 0000-0003-1472-1231 | - |
crisitem.author.orcid | 0000-0001-7461-1291 | - |
crisitem.author.orcid | 0000-0003-2403-4056 | - |
crisitem.author.orcid | 0000-0002-6557-211X | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | Oncology-NTUH | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
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