https://scholars.lib.ntu.edu.tw/handle/123456789/470970
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Wu X.-M. | en_US |
dc.contributor.author | YEN-HUNG LIN | en_US |
dc.contributor.author | Chen A. | en_US |
dc.contributor.author | Hsu T.-P. | en_US |
dc.contributor.author | YEN-WEN WU | en_US |
dc.contributor.author | HUNG-JU LIN | en_US |
dc.contributor.author | RON-BIN HSU | en_US |
dc.contributor.author | CHII-MING LEE | en_US |
dc.contributor.author | SHOEI-SHEN WANG | en_US |
dc.contributor.author | Lo M.-T. | en_US |
dc.contributor.author | YI-LWUN HO | en_US |
dc.contributor.author | MING-FONG CHEN | en_US |
dc.creator | Chen M.-F.;Ho Y.-L.;Lo M.-T.;SHOEI-SHEN WANG;Lee C.-M.;Hsu R.-B.;Lin H.-J.;Wu Y.-W.;Hsu T.-P.;Chen A.;Lin Y.-H.;Wu X.-M. | - |
dc.date.accessioned | 2020-03-05T08:37:45Z | - |
dc.date.available | 2020-03-05T08:37:45Z | - |
dc.date.issued | 2012-10 | - |
dc.identifier.issn | 0014-2972 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84866280411&doi=10.1111%2fj.1365-2362.2012.02698.x&partnerID=40&md5=b71f7b7d51028e051487ead50195427d | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/470970 | - |
dc.description.abstract | Objectives The goal of this study was designed to assess prognostic values of simultaneous measurement of adipocytokines in systolic heart failure (HF) patients. Methods Patients with HF manifestations and left ventricular ejection fraction (LVEF)?50% were selected in this study. Gender, age, medications and serum biochemical data were recorded upon admissions. Adipocytokines including adiponectin, leptin, resistin, visfatin and retinol binding protein-4 were measured. Results A total of 108 (83 males and 25 females) patients were enroled. The age was 62±15years and mean LVEF was 35%. Twenty patients died during 776±323days follow-up. In univariate analysis, mortality was found to be associated with the log-transformed values of serum resistin (β=5·616, P=0·04), log-transformed values of serum adiponectin (β=4·377, P=0·038), age (β=1·071, P<0·001), NTHA functional status (β=3·752, P=0·001) and body mass index (β=0·858, P=0·012). Patients with higher level of serum resistin were associated with higher mortality (P=0·012). In multivariate analysis, mortality is associated with log-transformed values of serum resistin (β=3·666, P=0·045), age (β=1·044, P=0·017) and NTHA functional status (β=2·541, P=0·025). Conclusions Serum resistin level was associated with higher mortality in systolic HF patients even after adjusting clinical parameters. Resistin may be an informative risk marker for systolic HF patients. ? 2012 The Authors. European Journal of Clinical Investigation ? 2012 Stichting European Society for Clinical Investigation Journal Foundation. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | European Journal of Clinical Investigation | en_US |
dc.subject | Adipocytokine; Adiponectin; Heart failure; Leptin; Resistin; Visfatin | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adiponectin; leptin; nicotinamide phosphoribosyltransferase; resistin; retinol binding protein 4; adult; aged; article; body mass; controlled study; female; follow up; functional status; heart left ventricle ejection fraction; human; major clinical study; male; mortality; priority journal; prognosis; systolic heart failure; Adipokines; Biological Markers; Chronic Disease; Female; Heart Failure, Systolic; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Prognosis; Risk Factors; Ventricular Dysfunction, Left | - |
dc.title | Prognostic significance of adipocytokines in systolic heart failure patients | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1111/j.1365-2362.2012.02698.x | - |
dc.identifier.pmid | 22712474 | - |
dc.identifier.scopus | 2-s2.0-84866280411 | - |
dc.relation.pages | 1079-1086 | en_US |
dc.relation.journalvolume | 42 | en_US |
dc.relation.journalissue | 10 | en_US |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Nuclear Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUHBH | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Biomedical Electronics and Bioinformatics | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-8153-1441 | - |
crisitem.author.orcid | 0000-0003-1520-1166 | - |
crisitem.author.orcid | 0000-0003-1046-2308 | - |
crisitem.author.orcid | 0000-0002-7794-497X | - |
crisitem.author.orcid | 0000-0002-1075-5787 | - |
crisitem.author.orcid | 0000-0003-3201-4143 | - |
crisitem.author.orcid | 0000-0002-8936-9570 | - |
crisitem.author.orcid | 0000-0001-6633-7632 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
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