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  1. NTU Scholars
  2. 醫學院
  3. 醫學系
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/470993
Title: Bloodstream infection in heart transplant recipients: 12-year experience at a university hospital in Taiwan
Authors: Hsu R.-B.
Chang C.-I.
Fang C.-T.
Chang S.-C.
SHOEI-SHEN WANG 
Chu S.-H.
Issue Date: 2011
Journal Volume: 40
Journal Issue: 6
Start page/Pages: 1362-1367
Source: European Journal of Cardio-thoracic Surgery
Abstract: 
Objective: Bloodstream infection (BSI) is a well-recognized problem and it affects 10-50% of solid organ transplant recipients. The purpose of this study was to assess the incidence and prognosis of BSI in heart transplant recipients at our hospital. Methods: The study is a retrospective chart review. Results: We diagnosed 101 episodes of BSI in 73 out of 306 heart transplant patients (24%) during the 12-year study period. BSI occurred at a median of 191 days (range 1-3376) after transplant and 50% occurred within 6 months after transplant. Most BSI episodes were nosocomial (73%), especially those occurring within the first month (94%). As far as pathogen was concerned, Gram-negative bacteria predominated (57%), followed by Gram-positive bacteria (34%), fungus (5%), anaerobics (2%), and cryptococcus (2%). Overall 30-day mortality rate was 30%. Death occurred in 36% (13/36) of the patients with early-onset BSI, 14% (2/14) of the patients with BSI in months 2-6, and 29% (15/51) of the patients with late-onset BSI. Mortality rate was over 50% in those patients with Pseudomonal infection, fungal infection, cryptococcal infection of central nervous system, lung infection, and severe sepsis. Compared to Western series, there was a high incidence of infections caused by Enterobacter species and Acinetobacter baumannii. Conclusions: There was a high incidence of BSI after heart transplantation in Taiwan, especially infections caused by Enterobacter species and A. baumannii. Mortality was high in patients with infection caused by Pseudomonas, Candida, and Cryptococcus and in patients with severe sepsis. ? 2011 European Association for Cardio-Thoracic Surgery.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-82655181287&doi=10.1016%2fj.ejcts.2011.02.033&partnerID=40&md5=ae397d0025dc84afcb71b94a39020781
https://scholars.lib.ntu.edu.tw/handle/123456789/470993
ISSN: 1010-7940
DOI: 10.1016/j.ejcts.2011.02.033
metadata.dc.subject.other: Acinetobacter baumannii; adolescent; adult; aged; anaerobic bacterium; article; bloodstream infection; central nervous system infection; child; comparative study; cryptococcosis; Cryptococcus; disease severity; Enterobacter; female; fungus; graft recipient; Gram negative bacterium; Gram positive bacterium; heart transplantation; hospital infection; human; incidence; infant; lung infection; major clinical study; male; mycosis; preschool child; priority journal; prognosis; Pseudomonas infection; school child; sepsis; surgical mortality; Taiwan; university hospital; Adolescent; Adult; Aged; Antibiotic Prophylaxis; Bacteremia; Child; Child, Preschool; Cross Infection; Epidemiologic Methods; Female; Gram-Negative Bacterial Infections; Heart Transplantation; Hospitals, University; Humans; Immunosuppression; Infant; Male; Middle Aged; Opportunistic Infections; Postoperative Period; Taiwan; Young Adult
[SDGs]SDG3
Appears in Collections:醫學系

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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

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開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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