https://scholars.lib.ntu.edu.tw/handle/123456789/473812
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Meng F.-Y. | en_US |
dc.contributor.author | JENG-YUH KO | en_US |
dc.contributor.author | PEI-JEN LOU | en_US |
dc.contributor.author | CHENG-PING WANG | en_US |
dc.contributor.author | TSUNG-LIN YANG | en_US |
dc.contributor.author | Chang C.-H. | en_US |
dc.contributor.author | YIH-LEONG CHANG | en_US |
dc.contributor.author | TSENG-CHENG CHEN | en_US |
dc.creator | Meng F.-Y.;Ko J.-Y.;Lou P.-J.;Wang C.-P.;Yang T.-L.;Chang C.-H.;Yih-Leong Chang;Chen T.-C. | - |
dc.date.accessioned | 2020-03-07T06:56:33Z | - |
dc.date.available | 2020-03-07T06:56:33Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1068-9265 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84865131633&doi=10.1245%2fs10434-011-2214-1&partnerID=40&md5=5cc3148a722095843f5d3a4d30fbbc73 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/473812 | - |
dc.description.abstract | Background. The determining risk factors for patients with squamous cell carcinoma of the hard palate are not well verified. Methods. Medical records from our facility of all patients with squamous cell carcinoma of the hard palate receiving curative surgery between March 2003 and May 2009 were reviewed. Results. Seventy-eight patients were enrolled in the study. The 5 year disease-free and overall survival rates were 49.8 and 49.7%, respectively. The 5 year disease-free and overall survival rates were statistically different between positive/close margins and negative margins (24.6% vs. 65.4%, P = 0.02; 20.1% vs. 63.1%, P = 0.001, respectively), with and without soft palate invasion (38.8% vs. 68.9%, P = 0.02; 27.4% vs. 77.5%, P = 0.001, respectively), and soft palate invasion patients with and without perineural invasion (10.4% vs. 52.8%, P = 0.02; 0% vs. 38.1%, P = 0.008, respectively). The rate of positive nodal metastasis for T3 and T4 tumors was 44%. For the tumor with soft palate invasion, the rate of positive nodal metastasis was 29%. After multivariate analyses, soft palate invasion and positive/close margins were the determining risk factors for disease-free and overall survival. Conclusions. Soft palate invasion and positive/close margins were the determining risk factors for disease-free and overall survival in patients with squamous cell carcinoma of the hard palate. Elective neck dissection is suggested for advanced primary tumors (T3 or T4) or tumors with soft palate invasion. ? 2012 Society of Surgical Oncology. | en_US |
dc.relation.ispartof | Annals of Surgical Oncology | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; aged; article; cancer invasion; cancer patient; cancer survival; disease free survival; female; human; lymph node metastasis; major clinical study; male; overall survival; palate disease; perineurium; retrospective study; risk factor; soft palate; squamous cell carcinoma; squamous cell carcinoma of the hard palate; treatment outcome; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Palatal Neoplasms; Palate, Hard; Retrospective Studies; Risk Factors; Survival Rate; Treatment Outcome | - |
dc.title | The determining risk factors for treatment outcomes in patients with squamous cell carcinoma of the hard palate | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1245/s10434-011-2214-1 | - |
dc.identifier.pmid | 22271207 | - |
dc.identifier.scopus | 2-s2.0-84865131633 | - |
dc.relation.pages | 2003-2010 | en_US |
dc.relation.journalvolume | 19 | en_US |
dc.relation.journalissue | 6 | en_US |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
crisitem.author.dept | Otolaryngology | - |
crisitem.author.dept | Otolaryngology-NTUH | - |
crisitem.author.dept | Otolaryngology | - |
crisitem.author.dept | Otolaryngology-NTUH | - |
crisitem.author.dept | Otolaryngology | - |
crisitem.author.dept | Otolaryngology-NTUH | - |
crisitem.author.dept | Otolaryngology | - |
crisitem.author.dept | Otolaryngology-NTUH | - |
crisitem.author.dept | Pathology | - |
crisitem.author.dept | Pathology-NTUH | - |
crisitem.author.dept | Pathology-NTUCC | - |
crisitem.author.dept | Otolaryngology | - |
crisitem.author.dept | Otolaryngology-NTUH | - |
crisitem.author.orcid | 0000-0002-2538-558X | - |
crisitem.author.orcid | 0000-0002-3383-8593 | - |
crisitem.author.orcid | 0000-0001-7872-1463 | - |
crisitem.author.orcid | 0000-0001-6521-8631 | - |
crisitem.author.orcid | 0000-0001-5309-0554 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 病理學科所 |
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