https://scholars.lib.ntu.edu.tw/handle/123456789/474199| Title: | Surveillance of Immunosuppression during Pregnancy after Heart Transplantation: Case Report | Authors: | Tsao C.-I. NAI-KUAN CHOU Chi N.-H. Huang S.-C. Tsan C.-Y. Wang C.-H. Yu H.-Y. Wu I.-H. Chen Y.-S. Shun C.-T. Wang S.-S. |
Issue Date: | 2016 | Publisher: | Elsevier USA | Journal Volume: | 48 | Journal Issue: | 3 | Start page/Pages: | 978-981 | Source: | Transplantation Proceedings | Abstract: | Background Transplantation and immunosuppressive drugs are major limitations to the success of pregnancy. In 1988, the first pregnancy after a heart transplant was reported, which has given female recipients the hope to give birth. During pregnancy, physiologic changes with increased blood volume and hemodilution may influence blood drug level. Case Report We reported our experience in monitoring on immunosuppressive drugs for 2 cases. Both of them underwent heart transplantation in 2006 and were 34 and 37 years old at time of pregnancy. For both cases, we frequently monitored the blood level and increased the dosage of immunosuppressive drugs accordingly. Both cases had uneventful pregnancy and delivery to healthy babies at the National Taiwan University Hospital in Taiwan. Their postpartum courses were uneventful as well. Conclusions We advocate adjusting the immunosuppressive dosage according to the blood level before pregnancy. ? 2016 Elsevier Inc. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84969920651&doi=10.1016%2fj.transproceed.2016.02.046&partnerID=40&md5=02121c14b44e388a12b31c612c98c653 https://scholars.lib.ntu.edu.tw/handle/123456789/474199 |
ISSN: | 0041-1345 | DOI: | 10.1016/j.transproceed.2016.02.046 | metadata.dc.subject.other: | aminophylline; candesartan hexetil; cyclosporin A; everolimus; fluindostatin; immunosuppressive agent; levothyroxine sodium; magnesium oxide; mycophenolate mofetil; nystatin; procaterol; steroid; tacrolimus; valaciclovir; immunosuppressive agent; adult; Article; cardiac graft rejection; case report; chylothorax; congestive cardiomyopathy; congestive heart failure; drug blood level; drug dose increase; drug monitoring; drug substitution; drug withdrawal; echocardiography; extracorporeal oxygenation; female; follow up; heart muscle biopsy; heart transplantation; human; human tissue; hypothyroidism; immunosuppressive treatment; intraaortic balloon pump; mitral valve regurgitation; mitral valve replacement; obstetric delivery; pregnancy; pregnancy test; priority journal; Taiwan; university hospital; graft rejection; immunosuppressive treatment; newborn; pregnancy complication; pregnancy outcome; procedures; Adult; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppression; Immunosuppressive Agents; Infant, Newborn; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome [SDGs]SDG3 |
| Appears in Collections: | 醫學系 |
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