https://scholars.lib.ntu.edu.tw/handle/123456789/474418
標題: | The application of ultrasound in detecting lymph nodal recurrence in the treated neck of head and neck cancer patients | 作者: | CHI-MAW LIN CHENG-PING WANG Chun-Nan Chen CHE-YI LIN Li T.-Y. Chou C.-H. Hsu Y.-C. Kuo P.-Y. TSUNG-LIN YANG PEI-JEN LOU JENG-YUH KO TSENG-CHENG CHEN |
公開日期: | 2017 | 出版社: | Nature Publishing Group | 卷: | 7 | 期: | 1 | 來源出版物: | Scientific Reports | 摘要: | Early detection of neck lymph node (LN) recurrence is paramount in improving the prognosis of treated head and neck cancer patients. Ultrasound (US) with US-guided fine needle aspiration (FNA) and core needle biopsy (CNB) have been shown to have great accuracy for LN diagnoses in the untreated neck. However, in the treated neck with fibrosis, their roles are not clarified. Here, we retrospectively review 153 treated head and neck cancer patients who had received US and US-guided FNA/CNB. In multivariate logistic regression analyses, size (short-axis diameter >0.8 cm) (odds ratio (OR) 4.19, P = 0.007), round shape (short/long axis ratio >0.5) (OR 3.44, P = 0.03), heterogeneous internal echo (OR 3.92, P = 0.009) and irregular margin (OR 7.32, P < 0.001) are effective US features in predicting recurrent LNs in the treated neck. However, hypoechogenicity (OR 2.38, P = 0.289) and chaotic/absent vascular pattern (OR 3.04, P = 0.33) are ineffective. US-guided FNA (sensitivity/specificity: 95.24%/97.92%) is effective in the treated neck, though with high non-diagnostic rate (29.69%). US-guided CNB (sensitivity/specificity: 84.62%/100%) is also effective, though with low negative predictive value (62.5%). Overall, US with US-guided FNA/CNB are still effective diagnostic tools for neck nodal recurrence surveillance. ? 2017 The Author(s). |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021241985&doi=10.1038%2fs41598-017-04039-3&partnerID=40&md5=5908bf64b91202ba65fcdaa18f31139f https://scholars.lib.ntu.edu.tw/handle/123456789/474418 |
ISSN: | 2045-2322 | DOI: | 10.1038/s41598-017-04039-3 | SDG/關鍵字: | adult; aged; diagnostic imaging; echography; female; fine needle aspiration biopsy; head and neck tumor; human; image guided biopsy; large core needle biopsy; lymph node; male; middle aged; pathology; procedures; retrospective study; sensitivity and specificity; tumor recurrence; young adult; Adult; Aged; Biopsy, Fine-Needle; Biopsy, Large-Core Needle; Female; Head and Neck Neoplasms; Humans; Image-Guided Biopsy; Lymph Nodes; Male; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Sensitivity and Specificity; Ultrasonography; Young Adult |
顯示於: | 醫學系 |
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