https://scholars.lib.ntu.edu.tw/handle/123456789/476413
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | CHEN-CHUNG LIU | en_US |
dc.contributor.author | Chen C.-H. | en_US |
dc.contributor.author | Hwu H.-G. | en_US |
dc.contributor.author | Shiu S.-Y. | en_US |
dc.contributor.author | Hua M.-S. | en_US |
dc.contributor.author | Chen C.-H. | en_US |
dc.contributor.author | TZUNG-JENG HWANG | en_US |
dc.contributor.author | CHIH-MIN LIU | en_US |
dc.contributor.author | MING-HSIEN HSIEH | en_US |
dc.contributor.author | Liu S.-K. | en_US |
dc.contributor.author | WEI J. CHEN | en_US |
dc.creator | Liu C.-C.;Chen C.-H.;Hwu H.-G.;Shiu S.-Y.;Hua M.-S.;Chen C.-H.;Hwang T.-J.;Liu C.-M.;Ming-Hsien Hsieh;Liu S.-K.;Chen W.J. | - |
dc.date.accessioned | 2020-03-17T06:22:49Z | - |
dc.date.available | 2020-03-17T06:22:49Z | - |
dc.date.issued | 2012 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/476413 | - |
dc.description.abstract | Background/Purpose: The intermediate course of schizophrenia is a complex intertwined with the heterogeneity of the illness. This article attempts to simplify this complexity using a hypothetical tripartite based on the profile of symptoms at 6 months after acute treatment. Methods: This is a prospective 5-year follow-up study including 163 schizophrenic inpatients in northern Taiwan comparing patients' demographic data at index admission, scores on the Positive and Negative Syndrome Scale (PANSS) for schizophrenia and social function scale measured at admission, 6-month follow-up, and annually, and scores on a neuropsychologic test battery measured approximately 5 years after recruitment. Results: Patients were grouped into three subtypes based on their sixth-month symptomatology by Generalized Association Plots, designated as remitted (RM), persistent delusion/hallucination (PDH), and markedly blunting (MB) groups. These three subtypes presented with similar positive symptom profiles at recruitment, yet during follow-up, the PDH group tended to maintain the highest risk of having worse clinical symptomatology, social functioning, and neuropsychologic functioning, and the RM was the best outcome group. Conclusion: This three-subtype model provides a practical reference to predict medium-term outcomes by the subject's response to acute treatment and serves as a model to sort out part of the heterogeneous nature of schizophrenia that still should be examined by further psychopharmacological, neurobiological, and genetic studies. ? 2012. | - |
dc.relation.ispartof | Journal of the Formosan Medical Association | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; article; controlled study; delusion; disease course; female; follow up; hallucination; human; major clinical study; male; neuropsychological test; outcome assessment; Positive and Negative Syndrome Scale; remission; schizophrenia; social interaction; Taiwan; Acute Disease; Adult; Chronic Disease; Female; Follow-Up Studies; Humans; Logistic Models; Male; Neuropsychological Tests; Prognosis; Prospective Studies; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index | - |
dc.title | Medium-term course and outcome of schizophrenia depicted by the sixth-month subtype after an acute episode | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.jfma.2011.01.007 | - |
dc.identifier.pmid | 22656397 | - |
dc.identifier.scopus | 2-s2.0-84862802978 | - |
dc.relation.pages | 265-274 | - |
dc.relation.journalvolume | 111 | - |
dc.relation.journalissue | 5 | - |
item.fulltext | no fulltext | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.dept | Neurobiology and Cognitive Science Center | - |
crisitem.author.dept | Center for Integrated Dementia Care | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Epidemiology and Preventive Medicine | - |
crisitem.author.dept | Public Health | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.orcid | 0000-0002-9290-110X | - |
crisitem.author.orcid | 0000-0001-7894-9484 | - |
crisitem.author.orcid | 0000-0001-7016-8990 | - |
crisitem.author.orcid | 0000-0002-3585-7843 | - |
crisitem.author.orcid | 0000-0001-5899-5870 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | Others: University-Level Research Centers | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫學系 |
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