https://scholars.lib.ntu.edu.tw/handle/123456789/478050
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Wu J.-Y. | en_US |
dc.contributor.author | PING-HUNG KUO | en_US |
dc.contributor.author | PI-CHUAN FAN | en_US |
dc.contributor.author | HUEY-DONG WU | en_US |
dc.contributor.author | FUH-YUAN SHIH | en_US |
dc.contributor.author | PAN-CHYR YANG | en_US |
dc.creator | Yang P.-C.;FUH-YUAN SHIH;Wu H.-D.;Fan P.-C.;Kuo P.-H.;Wu J.-Y. | - |
dc.date.accessioned | 2020-03-23T09:48:34Z | - |
dc.date.available | 2020-03-23T09:48:34Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1541-6933 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/478050 | - |
dc.description.abstract | Introduction: Myasthenic crisis is a great threat to patients with myasthenia gravis. Usage of non-invasive ventilation (NIV) to prevent intubation and timing of extubating of patients in myasthenic crisis are important issues though not well documented. Methods: To explore the factors predicting NIV success and extubation outcome in myasthenic crisis, we reviewed the records of 41 episodes of myasthenia crisis. Results: NIV was applied to 14 episodes of myasthenic crisis and eight (57.1%) of them were successfully prevented from intubation. An Acute Physiology and Chronic Health Evaluation (APACHE) II score of <6 and a serum bicarbonate level of <30 mmol/l were independent predictors of NIV success. For patients undergoing invasive mechanical ventilation, extubation failure was observed in 13 (39.4%) of 33 episodes, and the most common cause was sputum impaction due to a poor cough strength (61.5%). A maximal expiratory pressure (Pemax) of ?40 cmH2O was a good predictor of extubation success. Extubation failure led to poorer outcomes. Conclusions: NIV may be applied to those patients with a low APACHE II score and a lesser degree of metabolic compensation for respiratory acidosis. For patients undergoing invasive mechanical ventilation, extubation failure is associated with significant in-hospital morbidity in myasthenic crisis. Adequate levels of Pemax and cough strength correlate significantly with extubation success. ? 2007 Humana Press Inc. | - |
dc.relation.ispartof | Neurocritical Care | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | bicarbonate; immunosuppressive agent; steroid; adult; APACHE; article; assisted ventilation; bicarbonate blood level; clinical article; coughing; extubation; female; human; intubation; male; medical record review; myasthenia; myasthenic crisis; non invasive procedure; outcome assessment; plasmapheresis; prediction; priority journal; sputum; treatment failure; aged; artificial ventilation; cohort analysis; endotracheal intubation; intensive care; methodology; middle aged; myasthenia gravis; prediction and forecasting; respiratory failure; retrospective study; risk factor; treatment outcome; Aged; Cohort Studies; Female; Humans; Intensive Care; Intubation, Intratracheal; Male; Middle Aged; Myasthenia Gravis; Predictive Value of Tests; Respiration, Artificial; Respiratory Insufficiency; Retrospective Studies; Risk Factors; Treatment Outcome | - |
dc.title | The role of non-invasive ventilation and factors predicting extubation outcome in myasthenic crisis | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1007/s12028-008-9139-y | - |
dc.identifier.pmid | 18810663 | - |
dc.identifier.scopus | 2-s2.0-63249108477 | - |
dc.relation.pages | 35-42 | - |
dc.relation.journalvolume | 10 | - |
dc.relation.journalissue | 1 | - |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Integrated Diagnostics and Therapeutics-NTUH | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Clinical Medicine | - |
crisitem.author.dept | Clinical Pharmacy | - |
crisitem.author.dept | Oncology | - |
crisitem.author.dept | Biomedical Electronics and Bioinformatics | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0003-3756-3395 | - |
crisitem.author.orcid | 0000-0002-6974-971X | - |
crisitem.author.orcid | 0000-0001-6279-0384 | - |
crisitem.author.orcid | 0000-0002-7755-0110 | - |
crisitem.author.orcid | 0000-0001-6330-6048 | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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