https://scholars.lib.ntu.edu.tw/handle/123456789/478755
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Wang W.-K. | en_US |
dc.contributor.author | SHEY-YING CHEN | en_US |
dc.contributor.author | Liu I.-J. | en_US |
dc.contributor.author | CHUAN-LIANG KAO | en_US |
dc.contributor.author | Chen H.-L. | en_US |
dc.contributor.author | BOR-LUEN CHIANG | en_US |
dc.contributor.author | JANN-TAY WANG | en_US |
dc.contributor.author | WANG-HUEI SHENG | en_US |
dc.contributor.author | PO-REN HSUEH | en_US |
dc.contributor.author | Yang C.-F. | en_US |
dc.contributor.author | PAN-CHYR YANG | en_US |
dc.contributor.author | SHAN-CHWEN CHANG | en_US |
dc.creator | Wang W.-K.;Shey-Ying Chen;Liu I.-J.;Kao C.-L.;Chen H.-L.;Chiang B.-L.;Wang J.-T.;Sheng W.-H.;Hsueh P.-R.;Yang C.-F.;Yang P.-C.;Chang S.-C. | - |
dc.date.accessioned | 2020-03-24T09:08:00Z | - |
dc.date.available | 2020-03-24T09:08:00Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 1058-4838 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/478755 | - |
dc.description.abstract | Although viral replication and overwhelming immune responses are believed to contribute to the progression of severe acute respiratory syndrome (SARS), little is known about the temporal relationship between viral load, ribavirin, proinflammatory cytokines, and clinical progression. We report that ribavirin was not effective in reducing the SARS coronavirus load in 3 of 8 probable cases studied and that elevated levels of interleukin (IL)-6 and IL-8 subsequent to the peak viral load were found in 8 and 6 cases, respectively. The nadir lymphocyte count during lymphopenia, the peak level of lactate dehydrogenase, and the peak density of pulmonary infiltrates lag further behind the peak viral load by a median of 4, 5, and 3.5 days, respectively. These findings provide important information for therapeutic strategies to treat SARS. | - |
dc.relation.ispartof | Clinical Infectious Diseases | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | interleukin 6; interleukin 8; lactate dehydrogenase; ribavirin; adult; article; clinical article; disease course; drug efficacy; female; human; lung infiltrate; lymphocyte count; lymphocytopenia; male; priority journal; severe acute respiratory syndrome; virus load; virus replication; Adult; Antiviral Agents; Female; Humans; Interleukin-6; Interleukin-8; Male; Middle Aged; Ribavirin; SARS Virus; Severe Acute Respiratory Syndrome; Time Factors; Viral Load | - |
dc.title | Temporal relationship of viral load, ribavirin, interleukin (IL)-6, IL-8, and clinical progression in patients with severe acute respiratory syndrome | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1086/423808 | - |
dc.identifier.pmid | 15472864 | - |
dc.identifier.scopus | 2-s2.0-4744370932 | - |
dc.relation.pages | 1071-1075 | - |
dc.relation.journalvolume | 39 | - |
dc.relation.journalissue | 7 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Clinical Laboratory Sciences and Medical Biotechnology | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Clinical Medicine | - |
crisitem.author.dept | Oral Biology | - |
crisitem.author.dept | College of Life Science | - |
crisitem.author.dept | Immunology | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Center for Infection Control | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Medical Education-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Laboratory Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Clinical Medicine | - |
crisitem.author.dept | Clinical Pharmacy | - |
crisitem.author.dept | Oncology | - |
crisitem.author.dept | Biomedical Electronics and Bioinformatics | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Office of the Vice President | - |
crisitem.author.dept | Clinical Pharmacy | - |
crisitem.author.dept | Medical Education and Bioethics | - |
crisitem.author.orcid | 0000-0002-5855-6170 | - |
crisitem.author.orcid | 0000-0002-1020-2605 | - |
crisitem.author.orcid | 0000-0002-6705-0286 | - |
crisitem.author.orcid | 0000-0002-0924-3469 | - |
crisitem.author.orcid | 0000-0002-5605-7853 | - |
crisitem.author.orcid | 0000-0002-7502-9225 | - |
crisitem.author.orcid | 0000-0001-6330-6048 | - |
crisitem.author.orcid | 0000-0001-6505-4139 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | Administrative Unit | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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