https://scholars.lib.ntu.edu.tw/handle/123456789/481090
Title: | Nonintubated thoracoscopic lobectomy for lung cancer | Authors: | JIN-SHING CHEN YA-JUNG CHENG MING-HUI HUNG Tseng, Yu-Ding KE-CHENG CHEN Lee, Yung-Chie |
Issue Date: | 2011 | Journal Volume: | 254 | Journal Issue: | 6 | Start page/Pages: | 1038-1043 | Source: | Annals of Surgery | Abstract: | OBJECTIVE:: To evaluate the feasibility and safety of thoracoscopic lobectomy without endotracheal intubation. SUMMARY BACKGROUND DATA:: General anesthesia with single-lung ventilation is considered mandatory for thoracoscopic lobectomy for non-small cell lung cancer (NSCLC). Nonintubated thoracoscopic lobectomy has not been reported previously. METHODS:: From August 2009 through June 2010, some 30 consecutive patients with clinical stage I or II NSCLC were treated by nonintubated thoracoscopic lobectomy using epidural anesthesia, intrathoracic vagal blockade, and sedation. To evaluate the feasibility and safety of this novel technique, they were compared with a control group consisting of 30 consecutive patients with clinical stage I or II NSCLC who underwent thoracoscopic lobectomy using intubated general anesthesia from August 2008 through July 2009. RESULTS:: Collapse of the operative lung and inhibition of coughing were satisfactory in the nonintubated patients, induced by spontaneous breathing, and vagal blockade. Three patients in the nonintubated group required conversion to intubated-single lung ventilation because of persistent hypoxemia, poor epidural anesthesia pain control, and bleeding. One patient in each group was converted to thoracotomy because of bleeding. The 2 groups had comparable anesthesia durations, surgical durations, blood loss, and numbers of dissected lymph nodes. Patients who underwent nonintubated surgery had lower rates of sore throat (6.7% vs 40.0%, P = 0.002) and earlier resumption of oral intake (mean, 4.7 hours vs 18.8 hours, P < 0.001). Patients undergoing nonintubated surgery also had a trend toward better noncomplication rates (90% vs 66.7%, P = 0.057) and shorter postoperative hospital stays (mean, 5.9 days vs 7.1 days, P = 0.078). CONCLUSIONS:: Nonintubated thoracoscopic lobectomy is technically feasible and is as safe as lobectomy performed with intubation in highly selected patients. It can be a valid alternative of single-lung-ventilated thoracoscopic surgery in managing early-stage NSCLC. Copyright C © 2011 by Lippincott Williams & Wilkins. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-81855224644&doi=10.1097%2fSLA.0b013e31822ed19b&partnerID=40&md5=c6ac13ef08f000d3f503c9a7b4cff1a3 https://scholars.lib.ntu.edu.tw/handle/123456789/481090 |
ISSN: | 0003-4932 | DOI: | 10.1097/SLA.0b013e31822ed19b | SDG/Keyword: | bupivacaine; fentanyl; morphine; nonsteroid antiinflammatory agent; paracetamol; adult; article; artificial ventilation; breathing; cancer staging; cancer surgery; clinical article; controlled study; coughing; endotracheal tube; epidural anesthesia; female; forced expiratory volume; forced vital capacity; hospitalization; human; hypoxemia; intubation; lobectomy; lung collapse; lung non small cell cancer; lung ventilation; lymph node dissection; male; nonintubated thoracoscopic lobectomy; nose feeding; pain; pneumonia; postoperative hemorrhage; priority journal; sedation; sore throat; surgical technique; thoracotomy; tumor volume; vagus nerve; vomiting; Adult; Anesthesia, Epidural; Anesthesia, Intratracheal; Autonomic Nerve Block; Carcinoma, Non-Small-Cell Lung; Conscious Sedation; Feasibility Studies; Female; Hospitals, University; Humans; Length of Stay; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pneumonectomy; Postoperative Complications; Taiwan; Thoracoscopy; Vagus Nerve |
Appears in Collections: | 醫學系 |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.