https://scholars.lib.ntu.edu.tw/handle/123456789/481646
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lin Y.-C. | en_US |
dc.contributor.author | Wu D.-C. | en_US |
dc.contributor.author | JANG-MING LEE | en_US |
dc.contributor.author | Hsu H.-K. | en_US |
dc.contributor.author | Kao E.-L. | en_US |
dc.contributor.author | Yang C.-H. | en_US |
dc.contributor.author | Wu M.-T. | en_US |
dc.creator | Lin Y.-C.;Wu D.-C.;Jang-Ming Lee;Hsu H.-K.;Kao E.-L.;Yang C.-H.;Wu M.-T. | - |
dc.date.accessioned | 2020-03-31T03:59:45Z | - |
dc.date.available | 2020-03-31T03:59:45Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0304-3835 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33646846274&doi=10.1016%2fj.canlet.2005.06.010&partnerID=40&md5=fefa437414e53bf3799777fc79edc6c3 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/481646 | - |
dc.description.abstract | One hundred and forty-five ESCC patients and 352 controls were recruited from three hospitals in Taiwan to determine the association between esophageal squamous-cell-carcinoma (ESCC) and microsomal epoxide hydrolase (mEH) genotypes at Thy113His and His139Arg. Stratified by their exposures, the His113His genotype was a significant protective factor for ESCC in areca chewers and tobacco smokers. Stratified by His113 polymorphisms, the risk of contracting ESCC for participants with His113His who chewed areca and smoked was >50% less than for those with Thy113Thy. We suggest that the mEH His113His genotype can differentiate the association between smoking, areca chewing, and ESCC. ? 2005 Elsevier Ireland Ltd. All rights reserved. | - |
dc.relation.ispartof | Cancer Letters | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | epoxide hydrolase; adult; article; betel nut; cancer risk; controlled study; esophagus carcinoma; female; genetic polymorphism; genotype; human; major clinical study; male; mastication; priority journal; smoking; squamous cell carcinoma; statistical analysis; Taiwan; Adult; Areca; Carcinoma, Squamous Cell; Epoxide Hydrolases; Esophageal Neoplasms; Female; Genotype; Humans; Male; Microsomes; Middle Aged; Polymorphism, Genetic; Smoking; Taiwan; Areca; Nicotiana tabacum | - |
dc.title | The association between microsomal epoxide hydrolase genotypes and esophageal squamous-cell-carcinoma in Taiwan: Interaction between areca chewing and smoking | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.canlet.2005.06.010 | - |
dc.identifier.pmid | 16029924 | - |
dc.identifier.scopus | 2-s2.0-33646846274 | - |
dc.relation.pages | 281-288 | - |
dc.relation.journalvolume | 237 | - |
dc.relation.journalissue | 2 | - |
item.fulltext | no fulltext | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.openairetype | journal article | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.orcid | 0000-0001-9727-227X | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
Appears in Collections: | 醫學系 |
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