https://scholars.lib.ntu.edu.tw/handle/123456789/502721
標題: | Parvovirus B19 infection associated with the production of antineutrophil cytoplasmic antibody (ANCA) and anticardiolipin antibody (aCL) | 作者: | Chou T.N.K. Hsu T.-C. Chen R.-M. LIANG-IN LIN Tsay G.J. |
關鍵字: | aCL; ANCA; Autoimmune response; Parvovirus B19 infection | 公開日期: | 2000 | 卷: | 9 | 期: | 7 | 起(迄)頁: | 551-554 | 來源出版物: | Lupus | 摘要: | We described four patients who had clinical diagnosis of erythema infectiosum and presented with skin rash, polyarthralgia, polyarthritis, and mild fever. Anti-parvovirus B19 IgM and IgG antibodies were found in all four patients and parvovirus B19 DNA was detected in three of the four patients by polymerase chain reaction (PCR) in sera using standard methods. Anticardiolipin antibody (aCL) was positive in three of the four patients included three with anti-β2 glycoprotein I (β2GPI). The immunoglobulin isotype of aCL was found to be IgM. Anti-neutrophil cytoplasmic antibody (ANCA) included three p-ANCA and one c-ANCA was detected in all four patients by indirect immunofluoresence (IIF). Both anti-proteinase 3 (PR3) and anti-myeloperoxidase (MPO) antibodies were found in two patients whom had polyarthritis for more than 6 months. These data indicate parvovirus B19 may be linked to the induction of an autoimmune response. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/502721 | ISSN: | 0961-2033 | DOI: | 10.1177/096120330000900714 | SDG/關鍵字: | beta2 glycoprotein 1; cardiolipin antibody; enzyme antibody; immunoglobulin G antibody; immunoglobulin M antibody; myeloblastin; myeloperoxidase; neutrophil cytoplasmic antibody; protein antibody; virus antibody; virus DNA; adult; antibody production; arthralgia; article; autoimmunity; case report; clinical feature; disease association; erythema infectiosum; female; fever; human; immunofluorescence; male; Parvovirus; polyarthritis; priority journal; rash; Adult; Antibodies, Anticardiolipin; Antibodies, Antineutrophil Cytoplasmic; Arthritis; Autoantibodies; DNA, Viral; Erythema Infectiosum; Female; Fluorescent Antibody Technique, Indirect; Humans; Immunoglobulin G; Immunoglobulin M; Male; Parvovirus B19, Human; Polymerase Chain Reaction |
顯示於: | 醫學檢驗暨生物技術學系 |
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