https://scholars.lib.ntu.edu.tw/handle/123456789/504014
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Chou H-C. | en_US |
dc.contributor.author | SHU-WHA LIN | en_US |
dc.contributor.author | Chen W-W. | en_US |
dc.contributor.author | Ke W-M. | en_US |
dc.contributor.author | Chao P-H. | en_US |
dc.contributor.author | FEI-YUAN HSIAO | en_US |
dc.creator | Chou H-C.;Shu-Wha Lin;Chen W-W.;Ke W-M.;Chao P-H.;Hsiao F-Y. | - |
dc.date.accessioned | 2020-06-22T07:37:05Z | - |
dc.date.available | 2020-06-22T07:37:05Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/504014 | - |
dc.description.abstract | Objective: To investigate adherence to liver function monitoring as recommended in Taiwan's tuberculosis (TB) diagnosis and treatment guidelines for newly diagnosed TB patients.Design: Retrospective cohort study of the National Health Insurance Research Database (NHIRD), Taiwan, 2000-2011.Methods: From the NHIRD, we identified 11 397 newly diagnosed TB patients who initiated anti-tuberculosis treatment between 2000 and 2011 and categorised these into three groups: completely, partially and non-adherent. Logistic regression was used to explore potential factors associated with the adherence rate.Results: The completely adherent rate increased from 0.5% in 2000 to 9.2% in 2011, while the non-adherent rate decreased from 17.5% to 1.2%. Compared to the non-adherent group, patients with a history of liver disease (OR 4.36, 95%CI 1.92-9.87) and viral hepatitis (OR 9.39, 95%CI 1.47-60.19), as well as patients whose prescribing physicians were specialists in chest (OR 4.59, 95%CI 1.91-11.05), TB (OR 2.55, 95%CI 1.01-6.40) and infectious diseases (OR 3.93, 95%CI 1.08-14.31), had higher odds of being completely adherent to the guidelines.Conclusion: Our findings could serve as an important reference for developing effective strategies to improve adherence to guidelines and prevent patients from developing anti-tuberculosis drug-associated hepatotoxicity. ? 2014 The Union. | - |
dc.relation.ispartof | International Journal of Tuberculosis and Lung Disease | - |
dc.subject | Adherence; Hepatotoxicity; Liver function tests; Tuberculosis | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | tuberculostatic agent; tuberculostatic agent; adolescent; adult; aged; Article; child; cohort analysis; data base; female; human; infant; liver function test; logistic regression analysis; major clinical study; male; medical history; monitoring; newborn; population research; practice guideline; prescription; retrospective study; Taiwan; tuberculosis; virus hepatitis; drug effects; liver; Liver Diseases; liver function test; middle aged; pathophysiology; patient compliance; preschool child; statistical model; tuberculosis; young adult; Adolescent; Adult; Aged; Antitubercular Agents; Child; Child, Preschool; Female; Guideline Adherence; Humans; Infant; Liver; Liver Diseases; Liver Function Tests; Logistic Models; Male; Middle Aged; Patient Compliance; Retrospective Studies; Taiwan; Tuberculosis; Young Adult | - |
dc.title | Monitoring liver function among patients who initiated antituberculosis drugs in Taiwan, 2000-2011 | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.5588/ijtld.14.0155 | - |
dc.identifier.pmid | 25216841 | - |
dc.identifier.scopus | 2-s2.0-84907170238 | - |
dc.relation.pages | 1245_1251 | - |
dc.relation.journalvolume | 18 | - |
dc.relation.journalissue | 10 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Clinical Laboratory Sciences and Medical Biotechnology | - |
crisitem.author.dept | Clinical Pharmacy | - |
crisitem.author.dept | Pharmacy | - |
crisitem.author.dept | School of Pharmacy | - |
crisitem.author.orcid | 0000-0001-6748-5581 | - |
crisitem.author.orcid | 0000-0003-1660-9120 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫學檢驗暨生物技術學系 |
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