https://scholars.lib.ntu.edu.tw/handle/123456789/506303
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hsieh C.-H. | en_US |
dc.contributor.author | Shueng P.-W. | en_US |
dc.contributor.author | LI-YING WANG | en_US |
dc.contributor.author | Liao L.-J. | en_US |
dc.contributor.author | Lin Y.-C. | en_US |
dc.contributor.author | Kuo Y.-S. | en_US |
dc.contributor.author | Lo W.-C. | en_US |
dc.contributor.author | Tseng C.-F. | en_US |
dc.contributor.author | Tien H.-J. | en_US |
dc.contributor.author | Chou H.-L. | en_US |
dc.contributor.author | Hsieh Y.-P. | en_US |
dc.contributor.author | Wu L.-J. | en_US |
dc.contributor.author | Chen Y.-J. | en_US |
dc.date.accessioned | 2020-06-29T02:20:10Z | - |
dc.date.available | 2020-06-29T02:20:10Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1178-6930 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84897903834&doi=10.2147%2fOTT.S59998&partnerID=40&md5=d620021f6291eed4e8e170e665261f24 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/506303 | - |
dc.description.abstract | Background: The outcome of postoperative high- and intermediate-risk oral cavity cancer (OCC) patients receiving helical tomotherapy (HT) remains limited. Materials and methods: Between November 2006 and November 2012, 53 postoperative high- and intermediate-risk OCC patients treated with HT were enrolled. Results: The 4-year locoregional, local, and regional control rates were 66%, 76.4%, and 94.3%, respectively. The 4-year locoregional control rates of oral tongue and buccal mucosa cancer were 88.3% and 37.1%, respectively (P=0.012). Eleven (20.8%) patients experienced locoregional failure. In-field failure occurred in six of 53 (11.3%) in the primary area and three of 53 (5.7%) in the regional lymph-node area. No marginal failure was noted. Two of 53 (3.8%) experienced out-of-field failure. The rates of grade 3 dermatitis, mucositis, and dysphagia were 11%, 34%, and 13%, respectively. No grade 3 xerostomia was noted. Grade 2 xerostomia was 33% at month 6 and declined to 0 at month 48. A rate of 56% of grade 2 trismus at month 6 was noted, and declined to around 30% after 2 years. No grade 3 trismus was noted after 2 years. Conclusion: HT as a postoperative modality provided satisfying results, especially for xerostomia and trismus, and was impressive in high- and intermediate-risk OCC patients receiving postoperative HT. ? 2014 Hsieh et al. | - |
dc.publisher | DOVE Medical Press Ltd. | - |
dc.relation.ispartof | OncoTargets and Therapy | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | cisplatin; fluorouracil; folinic acid; adult; aged; anemia; article; cancer control; cancer radiotherapy; cheek mucosa; chemoradiotherapy; dysphagia; female; fistula; human; leukopenia; major clinical study; male; mouth squamous cell carcinoma; mucosa inflammation; oral surgery; photon therapy; postoperative care; radiation dermatitis; retrospective study; therapy effect; thrombocytopenia; tomotherapy; tongue cancer; treatment failure; trismus; xerostomia | - |
dc.title | Clinical effectiveness, toxicity, and failure patterns of helical tomotherapy for postoperative oral cavity cancer patients | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.2147/OTT.S59998 | - |
dc.identifier.scopus | 2-s2.0-84897903834 | - |
dc.relation.pages | 405-414 | - |
dc.relation.journalvolume | 7 | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
crisitem.author.dept | Physical Therapy | - |
crisitem.author.orcid | 0000-0003-3075-6872 | - |
crisitem.author.parentorg | College of Medicine | - |
Appears in Collections: | 物理治療學系所 |
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