https://scholars.lib.ntu.edu.tw/handle/123456789/510174
Title: | Automatic sleep staging in patients with obstructive sleep apnea using single-channel frontal EEG | Authors: | PEI-LIN LEE Huang, Y.-H. Lin, P.-C. Chiao, Y.-A. Hou, J.-W. Liu, H.-W. Huang, Y.-L. Liu, Y.-T. TZI-DAR CHIUEH |
Keywords: | Automatic sleep staging; Deep sleep; Electroencephalography obstructive sleep apnea; Light sleep; Polysomnography | Issue Date: | 2019 | Publisher: | American Academy of Sleep Medicine | Journal Volume: | 15 | Journal Issue: | 10 | Start page/Pages: | 1411-1420 | Source: | Journal of Clinical Sleep Medicine | Abstract: | Study Objectives: Reliable sleep staging is difficult to obtain from home sleep testing for diagnosis of obstructive sleep apnea (OSA), especially when it is self-applied. Hence, the current study aimed to develop a single frontal electroencephalography-based automatic sleep staging system (ASSS). Methods: The ASSS system was developed on a clinical dataset, with a high percentage of participants with OSA. The F4-M1 signal extracted from 62 participants (62.9% having OSA) was used to build a four-stage classifier. Performance of the ASSS was tested in a holdout set of 58 patients (60.3% having OSA) with epoch-by-epoch and whole-night agreement for sleep staging compared with expert scoring of polysomnography. Results: Mean all-stage percentage agreement was 75.52% (95% confidence interval, 72.90 to 78.13) (kappa 0.62; 95% confidence interval, 0.58 to 0.65), with mean percentage agreement for wake, light sleep, deep sleep (DS), and rapid eye movement of 78.04%, 70.97%, 83.65%, and 75.00%, respectively. The whole-night agreement was good-excellent (intraclass correlation coefficient, 0.74 to 0.88) for sleep onset latency, wake after sleep onset, total sleep time, and sleep efficiency. Compared to the non-OSA subset, the OSA subset had lower agreement for DS. Conclusions: Our results indicate that a single-channel F4-M1 based ASSS was sufficient for sleep staging in a population with a high percentage of participants with OSA. © 2019 American Academy of Sleep Medicine. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073049775&doi=10.5664%2fjcsm.7964&partnerID=40&md5=3fa465d467177f6be10925e3242ce054 https://scholars.lib.ntu.edu.tw/handle/123456789/510174 |
ISSN: | 15509389 | DOI: | 10.5664/jcsm.7964 | SDG/Keyword: | adult; Article; automatic sleep staging system; automation; controlled study; electroencephalography; female; human; major clinical study; male; middle aged; night sleep; polysomnography; REM sleep; scoring system; sleep disordered breathing; sleep latency; sleep stage; sleep time; slow wave sleep; stage 1 sleep; stage 2 sleep; staging; electroencephalography; pathophysiology; physiology; procedures; reproducibility; sleep disordered breathing; sleep stage; Taiwan; Electroencephalography; Female; Humans; Male; Middle Aged; Polysomnography; Reproducibility of Results; Sleep Apnea, Obstructive; Sleep Stages; Taiwan |
Appears in Collections: | 醫學系 |
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