https://scholars.lib.ntu.edu.tw/handle/123456789/510361
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | CHING-KAI LIN | en_US |
dc.contributor.author | I-SHIOW JAN | en_US |
dc.contributor.author | KAI-LUN YU | en_US |
dc.contributor.author | LIH-YU CHANG | en_US |
dc.contributor.author | Fan H.-J. | en_US |
dc.contributor.author | Wen Y.-F. | en_US |
dc.contributor.author | CHAO-CHI HO | en_US |
dc.date.accessioned | 2020-07-21T06:46:13Z | - |
dc.date.available | 2020-07-21T06:46:13Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 0929-6646 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077913695&doi=10.1016%2fj.jfma.2020.01.001&partnerID=40&md5=320f2db6d517970ca1e28554246ee05c | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/510361 | - |
dc.description.abstract | Background/Purpose: Rapid on-site cytologic evaluation (ROSE) has been shown to improve the diagnostic accuracy of endobronchial ultrasound-guided transbronchial biopsy (EBUS-TBB). However, ROSE by a cytopathologist or cytotechnologist is not always available during the procedure. The purposes of this study were to verify that a pulmonologist, after receiving training in cytology, could accurately assess an EBUS-TBB specimen on-site, and to evaluate the contribution of ROSE to EBUS-TBB. Methods: A retrospective chart review of patients who underwent EBUS-TBB for diagnosis of peripheral pulmonary lesions (PPLs) from January 2014 to June 2017 was performed. PPLs without a malignant diagnosis were excluded. The ROSE result determined by a pulmonologist was compared to the formal imprint cytologic report and pathologic report. The diagnostic accuracy of EBUS-TBB was also compared between those with and without ROSE. Results: Two hundred ninety-three patients who underwent 336 EBUS-TBB procedures for PPL diagnosis and were found to have proven malignancy were enrolled. Eighty-six procedures were performed with ROSE. With the formal imprint cytologic diagnosis as the standard, ROSE had 96.9% sensitivity, 68.2% specificity, 89.9% positive predictive value (PPV), 88.2% negative predictive value (NPV), and 89.5% diagnostic accuracy. With the formal pathologic result as the standard, ROSE had 88.2% sensitivity, 80% specificity, 97.1% PPV, 47.1% NPV, and 87.2% diagnostic accuracy, respectively. The diagnostic accuracy was significantly higher when ROSE was performed during EBUS-TBB (88.4% vs 68.0%, P < 0.001). Conclusion: A trained pulmonologist can interpret adequately cytologic smears on-site and effectively improve the accuracy of EBUS-TBB in the diagnosis of PPLs. ? 2020 Formosan Medical Association | en_US |
dc.publisher | Elsevier B.V. | en_US |
dc.relation.ispartof | Journal of the Formosan Medical Association | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | bronchodilating agent; fentanyl; lidocaine; midazolam; adult; aged; Article; bronchospasm; cancer cytodiagnosis; cancer patient; conscious sedation; controlled study; cytodiagnosis; diagnostic accuracy; diagnostic test accuracy study; diagnostic value; disease severity; endobronchial ultrasonography; female; human; human tissue; hypoxia; interventional ultrasonography; local anesthesia; lung cancer; major clinical study; male; malignant neoplasm; medical record review; oxygen therapy; peripheral lung lesion; pleura effusion; pneumothorax; predictive value; pulmonologist; rapid on site cytologic evaluation; retrospective study; sensitivity and specificity; thorax drainage; transbronchial biopsy; tumor volume; biopsy; bronchoscopy; diagnostic imaging; interventional ultrasonography; lung tumor; Biopsy; Bronchoscopy; Humans; Lung Neoplasms; Pulmonologists; Retrospective Studies; Ultrasonography, Interventional | - |
dc.title | Rapid on-site cytologic evaluation by pulmonologist improved diagnostic accuracy of endobronchial ultrasound-guided transbronchial biopsy | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.jfma.2020.01.001 | - |
dc.identifier.scopus | 2-s2.0-85077913695 | - |
item.cerifentitytype | Publications | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Medicine-NTUCC | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Laboratory Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUHHC | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUHHC | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-5171-4116 | - |
crisitem.author.orcid | 0000-0002-7936-5306 | - |
crisitem.author.orcid | 0000-0002-6506-9661 | - |
crisitem.author.orcid | 0000-0002-1318-5548 | - |
crisitem.author.orcid | 0000-0002-8156-2413 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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