https://scholars.lib.ntu.edu.tw/handle/123456789/512194
Title: | Idiopathic pulmonary fibrosis | Authors: | Wu C.-W. HAO-CHUN CHANG Chen T.-H. Huang H.-T. CHIA-JUNG LIU HAO-CHIEN WANG |
Issue Date: | 2018 | Publisher: | Society of Internal Medicine of Taiwan | Journal Volume: | 29 | Journal Issue: | 5 | Start page/Pages: | 283-291 | Source: | Journal of Internal Medicine of Taiwan | Abstract: | Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic, and idiopathic interstitial pneumonia. It's prone to elderlies, and the disease involvement is confined to the lungs. There has a unique pathological findings called usual interstitial pneumonia (UIP) that can be found in both histology and images on computer tomography (CT). To make the diagnosis of IPF, all known-cause of interstitial lung diseases such as environmental factors, medications, connective tissue diseases should be excluded first. In the past, IPF is considered as a poorly prognostic disease, while the median survival time was 0.9 year in Taiwan. However, as the pathogenesis is being studied, anti-fibrotic drugs (nintedanib and pirfenidone) have been developed. They were proved to be effective to decrease lung function decline in some large-scale studies. Moreover, there are more ongoing studies among IPF trying to improve prognosis of IPF patients. ? 2018 Society of Internal Medicine of Taiwan. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85058212885&doi=10.6314%2fJIMT.201810-29%285%29.02&partnerID=40&md5=76672064ef145ebce011e7367a484342 https://scholars.lib.ntu.edu.tw/handle/123456789/512194 |
ISSN: | 1016-7390 | DOI: | 10.6314/JIMT.201810-29(5).02 | SDG/Keyword: | nintedanib; pirfenidone; Article; computer assisted tomography; disease course; environmental factor; fibrosing alveolitis; histology; human; internal medicine; interstitial pneumonia; lung fibrosis; lung function; median survival time; prognosis |
Appears in Collections: | 醫學系 |
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