https://scholars.lib.ntu.edu.tw/handle/123456789/512289
標題: | Preadmission tracheostomy is associated with better outcomes in patients with prolonged mechanical ventilation in the postintensive care respiratory care setting | 作者: | CHUN-TA HUANG JOU-WEI LIN SHENG-YUAN RUAN CHUNG-YU CHEN CHONG-JEN YU |
公開日期: | 2017 | 出版社: | Elsevier B.V. | 卷: | 116 | 期: | 3 | 起(迄)頁: | 169-176 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Background/purpose Prolonged mechanical ventilation (PMV) is the most common situation where tracheostomy is indicated for intensive care unit (ICU) patients. However, it is unknown if this procedure confers survival benefits on PMV patients in a post-ICU setting. Methods Patients who were admitted to the specialized weaning unit from 2005 to 2008 and received PMV were included in this study. On admission, data pertaining to patient characteristics, physiologic status, and type of artificial airway (tracheostomy vs. no tracheostomy) were obtained. Outcomes of tracheostomized and nontracheostomized patients were evaluated using multivariate Cox proportional hazards and propensity score-matching models. The primary outcome of interest was 1-year survival. Results A total of 401 patients (mean age 74.4?years, 204 male) were identified. In multivariate analyses, higher Acute Physiology and Chronic Health Evaluation II score [hazard ratio (HR)?=?1.061, 95% confidence interval (CI)?=?1.016–1.107] and presence of comorbidities, including congestive heart failure (HR?=?1.562, 95% CI?=?1.119–2.181), malignancy (HR?=?1.942, 95% CI?=?1.306–2.885), and liver cirrhosis (HR?=?2.373, 95% CI?=?1.015–5.544), were independently associated with 1-year mortality. An association between having tracheostomy and a better 1-year outcome was observed (HR?=?0.625, 95% CI?=?0.453–0.863). The matched cohort study also demonstrated a favorable 1-year survival for tracheostomized patients, and these patients had significantly lower in-hospital mortality (24% vs. 36%, p?=?0.049) and risk of ventilator-associated pneumonia (10% vs. 20%, p?=?0.030) than nontracheostomized ones. Conclusion Preadmission tracheostomy may be associated with better outcomes of PMV patients in a post-ICU respiratory care setting. The findings suggest that this procedure should be recommended before PMV patients are transferred to specialized weaning units. ? 2016 |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85002688842&doi=10.1016%2fj.jfma.2016.05.005&partnerID=40&md5=d38e98e7766e64e2eb2f08e668fd3880 https://scholars.lib.ntu.edu.tw/handle/123456789/512289 |
ISSN: | 0929-6646 | DOI: | 10.1016/j.jfma.2016.05.005 | SDG/關鍵字: | aged; APACHE; Article; artificial ventilation; cohort analysis; comorbidity; congestive heart failure; controlled study; critical care outcome; diabetes mellitus; female; heart failure; hospital mortality; human; intensive care; length of stay; liver cirrhosis; major clinical study; male; malignant neoplasm; mortality; prognosis; respiratory care; respiratory failure; respiratory tract disease; sex difference; tracheostomy; ventilator associated pneumonia; ventilator weaning; hospital mortality; intensive care unit; middle aged; multivariate analysis; Pneumonia, Ventilator-Associated; statistical model; survival analysis; Taiwan; time factor; ventilator weaning; very elderly; Aged; Aged, 80 and over; Cohort Studies; Female; Hospital Mortality; Humans; Intensive Care Units; Length of Stay; Logistic Models; Male; Middle Aged; Multivariate Analysis; Pneumonia, Ventilator-Associated; Survival Analysis; Taiwan; Time Factors; Tracheostomy; Ventilator Weaning |
顯示於: | 醫學系 |
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