https://scholars.lib.ntu.edu.tw/handle/123456789/512401
標題: | Outcome of stage IV cancer patients receiving in-hospital cardiopulmonary resuscitation: a population-based cohort study | 作者: | MENG-RUI LEE KAI-LUN YU HUNG-YANG KUO TSUNG-HAO LIU JEN-CHUNG KO JAW-SHIUN TSAI JANN-YUAN WANG |
公開日期: | 2019 | 出版社: | Nature Publishing Group | 卷: | 9 | 期: | 1 | 起(迄)頁: | 9478 | 來源出版物: | Scientific Reports | 摘要: | The effects of cardiopulmonary resuscitation (CPR) on patients with advanced cancer remain to be elucidated. We identified a cohort of patients with stage-IV cancer who received in-hospital CPR from the Taiwan Cancer Registry and National Health Insurance claims database, along with a matched cohort without cancer who also received in-hospital CPR. The main outcomes were post-discharge survival and in-hospital mortality. In total, 3,446 stage-IV cancer patients who underwent in-hospital CPR after cancer diagnosis were identified during January 2009–June 2014. A vast majority of the patients did not survive to discharge (n = 2,854, 82.8%). The median post-discharge survival was 22 days; 10.1% (n = 60; 1.7% of all patients) of the hospital survivors received anticancer therapy after discharge. We created 1:1 age–, sex–, Charlson comorbidity index (CCI)–, and year of CPR–matched noncancer and stage-IV cancer cohorts (n = 3,425 in both; in-hospital mortality rate = 82.1% and 82.8%, respectively). Regression analysis showed that the stage-IV cancer cohort had shorter post-discharge survival than did the noncancer cohort. The outcome of patients with advanced cancer was poor. Even among the survivors, post-discharge survival was short, with only few patients receiving further anticancer therapy. ? 2019, The Author(s). |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068265344&doi=10.1038%2fs41598-019-45977-4&partnerID=40&md5=088514718783552f045ca88c52d4e3c1 https://scholars.lib.ntu.edu.tw/handle/123456789/512401 |
ISSN: | 2045-2322 | DOI: | 10.1038/s41598-019-45977-4 | SDG/關鍵字: | aged; cancer staging; disease free survival; female; hospital discharge; hospital mortality; human; male; middle aged; mortality; neoplasm; resuscitation; retrospective study; survival rate; very elderly; Aged; Aged, 80 and over; Cardiopulmonary Resuscitation; Disease-Free Survival; Female; Hospital Mortality; Humans; Male; Middle Aged; Neoplasm Staging; Neoplasms; Patient Discharge; Retrospective Studies; Survival Rate |
顯示於: | 醫學系 |
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