https://scholars.lib.ntu.edu.tw/handle/123456789/512497
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | CHIN-CHUNG SHU | en_US |
dc.contributor.author | JANN-TAY WANG | en_US |
dc.contributor.author | JANN-YUAN WANG | en_US |
dc.contributor.author | LI-NA LEE | en_US |
dc.contributor.author | CHONG-JEN YU | en_US |
dc.creator | Shu C.-C.;Wang J.-T.;Jann-Yuan Wang;Lee L.-N.;Yu C.-J. | - |
dc.date.accessioned | 2020-08-13T05:24:24Z | - |
dc.date.available | 2020-08-13T05:24:24Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1471-2334 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-79951700135&doi=10.1186%2f1471-2334-11-46&partnerID=40&md5=7c7e20e1ac6a275bde717b1dc98cafa2 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/512497 | - |
dc.description.abstract | Background: Outcomes for hospitalized patients with tuberculous pleurisy (TP) have rarely been reported, and whether or not pulmonary involvement affects outcomes is uncertain. This study aimed to analyze the in-hospital mortality rate of culture-confirmed TP with an emphasis on the clinical impact of pulmonary involvement.Methods: Patients who were hospitalized for pleural effusion (PE) of unconfirmed diagnosis and finally diagnosed as TP were identified. We classified them according to the disease extent: isolated pleurisy (isolated pleurisy group) and pleurisy with pulmonary involvement (pleuro-pulmonary group).Results: Among the 205 patients hospitalized before the diagnosis was established, 51 (24.9%) belonged to the isolated pleurisy group. Compared to the pleuro-pulmonary group, patients in the isolated pleurisy group were younger, had fewer underlying co-morbidities, and presented more frequently with fever and chest pain. Fewer patients in the isolated pleurisy group had hypoalbuminemia (< 3.5 g/dL) and anemia. The two groups were similar with regards to PE analysis, resistance pattern, and timing of anti-tuberculous treatment. Patients who had a typical pathology of TP on pleural biopsy received anti-tuberculous treatment earlier than those who did not, and were all alive at discharge. The isolated pleurisy group had a lower in-hospital mortality rate, a shorter length of hospital stay and better short-term survival. In addition, the presence of underlying comorbidities and not receiving anti-tuberculous treatment were associated with a higher in-hospital mortality rate.Conclusion: In culture-confirmed tuberculous pleurisy, those with pulmonary involvement were associated with a higher in-hospital mortality rate. A typical pathology for TP on pleura biopsy was associated with a better outcome. ? 2011 Shu et al; licensee BioMed Central Ltd. | - |
dc.relation.ispartof | BMC Infectious Diseases | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | albumin; ethambutol; isoniazid; pyrazinamide; rifampicin; adult; age; aged; antibiotic therapy; article; cause of death; clinical assessment; clinical evaluation; comorbidity; controlled study; differential diagnosis; female; fever; gastrointestinal hemorrhage; granulomatous inflammation; histopathology; hospital discharge; hospital patient; human; Human immunodeficiency virus infection; hypoalbuminemia; length of stay; lung tuberculosis; major clinical study; male; multidrug resistant tuberculosis; multiple organ failure; Mycobacterium tuberculosis; outcome assessment; patient care; pleura biopsy; pleura effusion; prognosis; respiratory failure; retrospective study; sex difference; sputum culture; survival rate; thorax pain; tuberculous pleurisy; biopsy; hospital; isolation and purification; lung; lung tuberculosis; middle aged; mortality; Mycobacterium tuberculosis; pathology; pleura; treatment outcome; tuberculous pleurisy; Adult; Aged; Aged, 80 and over; Biopsy; Female; Hospitals; Humans; Lung; Male; Middle Aged; Mycobacterium tuberculosis; Pleura; Treatment Outcome; Tuberculosis, Pleural; Tuberculosis, Pulmonary | - |
dc.title | In-hospital outcome of patients with culture-confirmed tuberculous pleurisy: Confirmedlinical impact of pulmonary involvement | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1186/1471-2334-11-46 | - |
dc.identifier.pmid | 21338482 | - |
dc.identifier.scopus | 2-s2.0-79951700135 | - |
dc.relation.pages | 46 | - |
dc.relation.journalvolume | 11 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Center for Infection Control | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUHHC | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Laboratory Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | National Taiwan University Hospital Hsin-Chu Branch | - |
crisitem.author.dept | NTU BioMedical Park Hospital | - |
crisitem.author.orcid | 0000-0003-0311-5148 | - |
crisitem.author.orcid | 0000-0002-0924-3469 | - |
crisitem.author.orcid | 0000-0003-3406-366X | - |
crisitem.author.orcid | 0000-0002-7654-2450 | - |
crisitem.author.orcid | 0000-0001-5664-9392 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital Hsin-Chu Branch | - |
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