https://scholars.lib.ntu.edu.tw/handle/123456789/513177
標題: | Magnetic resonance imaging following endoscopic nasopharyngectomy with a potassium-titanyl-phosphate (KTP) laser for early locally recurrent nasopharyngeal carcinoma | 作者: | YA-FANG CHEN YU-FEN WANG CHENG-PING WANG JENG-YUH KO CHUN-WEI WANG HON-MAN LIU |
公開日期: | 2013 | 卷: | 55 | 期: | 11 | 起(迄)頁: | 1413-1421 | 來源出版物: | Neuroradiology | 摘要: | Introduction: This study aims to investigate the spectrum of magnetic resonance imaging (MRI) features following endoscopic potassium-titanyl- phosphate (KTP) laser nasopharyngectomy. Methods: From January 2005 to December 2010, a total of 35 patients underwent KTP laser nasopharyngectomy for early recurrent NPC (rT1 or rT2) at our institute. Those who were lost to follow-up (N = 2) were excluded. Among the remaining patients, ten were proved to have locally recurrent disease and the other 23 not locally recurrent within 2 years of postoperative follow-up. Their serial MRIs were evaluated. Results: Postoperative nasopharyngeal mucosal changes were present in all of the subjects on first follow-up MRI, ranged from focal mucosal thinning (19/33, 57.6 %), focal mucosal thickening (8/33, 24.2 %) to mixed thinning and thickening (6/33, 18.2 %). Nasopharyngeal submucosal soft tissue volume loss was found in 23 (23/33, 69.7 %), and parapharyngeal soft tissue necrosis was found in 3 (3/33, 9.1 %). Postoperative bone marrow change involved the clivus in 31 (31/33, 93.9 %) and the petrous or pterygoid in 17 (17/33, 51.5 %). There were no significant differences between the two groups in the changes of mucosa, adjacent soft tissue, and skull base on the first MRI. The evaluation of serial MRIs disclosed that the patients in the recurrent group were more likely to develop new or enlarging mucosal masses (p = 0.01) and enlarging skull base changes (p = 0.0001). Conclusions: KTP laser nasopharyngectomy induces mucosal and skull base changes that could be misinterpreted as tumor progression on early postoperative MRI scans. Sequential imaging is required to distinguish between postoperative changes and progressive disease. ? 2013 Springer-Verlag Berlin Heidelberg. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/513177 | ISSN: | 0028-3940 | DOI: | 10.1007/s00234-013-1283-1 | SDG/關鍵字: | gadodiamide; adult; aged; article; bone marrow; cancer growth; cancer recurrence; clinical article; clivus; controlled study; ear nose throat surgery; early cancer; endoscopic potassium titanyl phosphate laser nasopharyngectomy; endoscopic surgery; female; human; laser surgery; male; mucosa; nasopharynx carcinoma; nuclear magnetic resonance imaging; patient selection; petrous bone; postoperative complication; postoperative mucosa change; postoperative period; priority journal; retrospective study; skull base; soft tissue; tissue necrosis; Adult; Aged; Combined Modality Therapy; Female; Humans; Lasers, Solid-State; Magnetic Resonance Imaging; Male; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Pharyngectomy; Retrospective Studies; Surgery, Computer-Assisted; Treatment Outcome |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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