https://scholars.lib.ntu.edu.tw/handle/123456789/514500
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | RUOH-FANG YEN | en_US |
dc.contributor.author | Yen M.-F. | en_US |
dc.contributor.author | RUEY-LONG HONG | en_US |
dc.contributor.author | KAI-YUAN TZEN | en_US |
dc.contributor.author | Chien C.-R. | en_US |
dc.contributor.author | Chen, Tony Hsiu Hsi | en_US |
dc.creator | Ruoh-Fang Yen;Yen M.-F.;Hong R.-L.;Tzen K.-Y.;Chien C.-R.;Chen T.H.-H. | - |
dc.date.accessioned | 2020-09-23T06:22:36Z | - |
dc.date.available | 2020-09-23T06:22:36Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1076-6332 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/514500 | - |
dc.description.abstract | Rationale and Objectives: 18-Fluoro-2-deoxyglucose (18F-FDG) positron emission tomography (PET) is effective but costly in the early detection of recurrence for nasopharyngeal carcinoma (NPC) in patients after treatment. In this study, we developed a decision tree model to analyze the cost utility of 18F-FDG PET in detecting loco-regional recurrences for NPC patients after therapy. Materials and Methods: The analysis for cost utility is based on the decision-tree model for three different strategies: 1) magnetic resonance imaging (MRI)-only, 2) PET-only, and 3) MRI-PET (performing PET if MRI result is uncertain). Sensitivity analyses have been performed to examine changes in the cost ratio of PET/MRI and the probability of uncertain MRI. Results: After inputting the data for utilities and life expectancies into the decision tree model, the quality-adjusted life expectancies turn out to be 16.16 quality-adjusted life-years (QALYs) for strategy 1, 16.70 QALYs for strategy 2, and 17.35 QALYs for strategy 3. The additional cost per additional QALYs for strategy 3 relative to strategy 1 is calculated to be US $462. Strategy 3 dominates over strategy 2 because strategy 3 costs less and yields more QALYs than strategy 2. If the cost ratio of PET/MRI is less than 1.85 or the probability of uncertain MRI is greater than 73%, then the PET-only strategy becomes more cost-effective than the MRI-PET strategy. Conclusion: Our analysis shows that the MRI-PET strategy is the most cost-effective for now. It is likely the PET-only strategy will become the most cost-effective for recurrent NPC in patients in the near future as the cost of PET has decreased in a faster rate than the cost of MRI. ? 2009 AUR. | - |
dc.relation.ispartof | Academic Radiology | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | fluorodeoxyglucose f 18; adult; article; clinical article; controlled study; cost benefit analysis; cost utility analysis; decision tree; diagnostic accuracy; early diagnosis; female; human; life expectancy; male; nasopharynx carcinoma; nuclear magnetic resonance imaging; outcome assessment; positron emission tomography; priority journal; probability; quality adjusted life year; recurrent cancer; sensitivity analysis; visual analog scale; Adult; Cost-Benefit Analysis; Female; Fluorodeoxyglucose F18; Health Care Costs; Humans; Male; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Positron-Emission Tomography; Radiopharmaceuticals; Taiwan | - |
dc.title | The Cost-utility Analysis of 18-Fluoro-2-Deoxyglucose Positron Emission Tomography in the Diagnosis of Recurrent Nasopharyngeal Carcinoma | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.acra.2008.06.012 | - |
dc.identifier.pmid | 19064212 | - |
dc.identifier.scopus | 2-s2.0-57049084026 | - |
dc.relation.pages | 54-60 | - |
dc.relation.journalvolume | 16 | - |
dc.relation.journalissue | 1 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Nuclear Medicine-NTUH | - |
crisitem.author.dept | Oncology | - |
crisitem.author.dept | Institute of Health Data Analytics and Statistics | - |
crisitem.author.dept | Public Health | - |
crisitem.author.orcid | 0000-0003-1648-6482 | - |
crisitem.author.orcid | 0000-0001-8100-7914 | - |
crisitem.author.orcid | 0000-0002-5657-8579 | - |
crisitem.author.orcid | 0000-0002-5799-6705 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Public Health | - |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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