https://scholars.lib.ntu.edu.tw/handle/123456789/514566
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Kao C.-H. | en_US |
dc.contributor.author | Tsai S.-C. | en_US |
dc.contributor.author | Wang J.-J. | en_US |
dc.contributor.author | Ho Y.-J. | en_US |
dc.contributor.author | RUOH-FANG YEN | en_US |
dc.contributor.author | Ho S.-T. | en_US |
dc.creator | Kao C.-H.;Tsai S.-C.;Wang J.-J.;Ho Y.-J.;Ruoh-Fang Yen;Ho S.-T. | - |
dc.date.accessioned | 2020-09-23T06:22:50Z | - |
dc.date.available | 2020-09-23T06:22:50Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 0008-543X | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/514566 | - |
dc.description.abstract | BACKGROUND. The diagnostic accuracy of combined computed tomography (CT) and technetium 99m tetrofosmin (Tc-TF) single photon emission computed tomography (SPECT) of head and neck to differentiate recurrent or residual nasopharyngeal carcinomas (NPCs) from benign lesions after radiotherapy was evaluated and compared with positron emission tomography (PET) with 18-fluoro-2-deoxyglucose (FDG). METHODS. Four months after radiotherapy, 36 patients with NPC underwent Tc-TF SPECT and CT of head and neck to differentiate recurrent or residual NPC from benign lesions. Histopathologic examinations were performed on nasopharyngeal biopsies of all 36 patients. RESULTS. Based on the biopsy results, the sensitivity, specificity, and accuracy of Tc-TF SPECT were 64%, 96%, and 86%, respectively, for differentiation of recurrent or persistent NPC from benign lesions. For CT and FDG-PET, the sensitivity, specificity, and accuracy were 73%, 88%, and 83% and 100%, 96%, 97%, respectively. For the 27 patients with NPC whose Tc-TF SPECT and CT results were congruent, the combination of Tc-TF SPECT and CT had the same sensitivity, specificity, and accuracy (100%, 96%, and 96%) as FDG-PET. For the nine patients with NPC with incongruent Tc-TF SPECT and CT results, FDG-PET correctly differentiated two benign lesions from seven recurrent/residual NPCs. CONCLUSIONS. Although, FDG-PET is the best tool for detecting recurrent or residual NPC, combined congruent Tc-TF SPECT and CT results achieved the same accuracy as FDG-PET. Therefore, we concluded that FDG-PET could be considered only when Tc-TF SPECT and CT give incongruent results. ? 2001 American Cancer Society. | - |
dc.relation.ispartof | Cancer | - |
dc.subject | 18-Fluoro-2-deoxyglucose; Computed tomography; Nasopharyngeal carcinoma; Positron emission tomography; Single photon emission computed tomography; Technetium 99m tetrofosmin | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | fluorodeoxyglucose f 18; tetrofosmin tc 99m; adult; aged; article; cancer diagnosis; clinical article; clinical trial; computer assisted tomography; controlled clinical trial; controlled study; diagnostic accuracy; diagnostic imaging; female; histopathology; human; intermethod comparison; male; nasopharynx carcinoma; positron emission tomography; priority journal; reliability; single photon emission computer tomography; Adolescent; Adult; Aged; Carcinoma; Diagnosis, Differential; Drug Resistance, Neoplasm; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Organophosphorus Compounds; Organotechnetium Compounds; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | - |
dc.title | Comparing 18-fluoro-2-deoxyglucose positron emission tomography with a combination of technetium 99m tetrofosmin single photon emission computed tomography and computed tomography to detect recurrent or persistent nasopharyngeal carcinomas after radiotherapy | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1002/1097-0142(20010715)92:2<434 | - |
dc.identifier.pmid | 11466699 | - |
dc.identifier.scopus | 2-s2.0-0035878910 | - |
dc.relation.pages | 434-439 | - |
dc.relation.journalvolume | 92 | - |
dc.relation.journalissue | 2 | - |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Nuclear Medicine-NTUH | - |
crisitem.author.orcid | 0000-0003-1648-6482 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學院附設醫院 (臺大醫院) |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。