https://scholars.lib.ntu.edu.tw/handle/123456789/514573
標題: | Comparison and discrepancy of 18F-2-Deoxyglucose positron emission tomography and Tc-99m MDP bone scan to detect bone metastases | 作者: | Kao C.-H. Hsieh J.-F. Tsai S.-C. Ho Y.-J. RUOH-FANG YEN |
關鍵字: | 18F-2-deoxyglucose positron emission tomography; Bone metastases; Tc-99m MDP bone scan | 公開日期: | 2000 | 卷: | 20 | 期: | 3 B | 起(迄)頁: | 2189-2192 | 來源出版物: | Anticancer Research | 摘要: | The purpose of this study was to evaluate the usefulness of positron emission tomography with 18F-2-deoxyglucose (FDG-PET) for the detection of malignant bone metastases, and to compare FDG-PET results with conventional technetium-99m methylene diophosphate (Tc-99m MDP) bone scan findings. Twenty-four patients (10 females, 14 males, ages: 39-71 years) with biopsy-proven malignancy and suspected bone metastases, underwent whole body FDG-PET and bone scan to detect bone metastases. Bone metastases were established in 39 discordant bone lesions by histopathological examination of biopsy samples, MRI/CT and follow-up bone. scan/FDG-PET findings showing progressively and extensively widespread bone lesions. A total of 98 bone lesions found on either FDG-PET or bone scan were evaluated For 39 bone lesions with discordant findings between FDG-PET and bone scan, histopathological examination, MRI/CT and follow-up bone scan/FDG-PET findings revealed 8 metastatic and 0 benign bone lesions with positive FDG-PET findings, not detected on bone scan. Eleven metastatic and 20 benign bone lesions with positive bone scan findings were not detected on FDG-PET. FDG-PET has a better specificity, but a lower sensitivity for detecting malignant bone metastases when compared with bone scan. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/514573 | ISSN: | 0250-7005 | SDG/關鍵字: | fluorodeoxyglucose f 18; medronate technetium tc 99m; adult; aged; article; bone lesion; bone metastasis; bone scintiscanning; cancer diagnosis; clinical article; clinical trial; computer assisted tomography; diagnostic value; female; histopathology; human; intermethod comparison; male; nuclear magnetic resonance imaging; positron emission tomography; priority journal; scintillation camera; whole body scanner; Adult; Aged; Bone and Bones; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Diagnosis, Differential; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Prostatic Neoplasms; Radiopharmaceuticals; Sensitivity and Specificity; Technetium Tc 99m Medronate; Tomography, Emission-Computed |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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