https://scholars.lib.ntu.edu.tw/handle/123456789/514635
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Tsai H.-H. | en_US |
dc.contributor.author | BO-CHING LEE | en_US |
dc.contributor.author | Huang C.-Y. | en_US |
dc.contributor.author | LI-KAI TSAI | en_US |
dc.contributor.author | SUNG-CHUN TANG | en_US |
dc.contributor.author | JIANN-SHING JENG | en_US |
dc.contributor.author | YA-FANG CHEN | en_US |
dc.creator | Tsai H.-H.;Lee B.-C.;Huang C.-Y.;Tsai L.-K.;Tang S.-C.;Jeng J.-S.;Ya-Fang Chen | - |
dc.date.accessioned | 2020-09-23T08:35:38Z | - |
dc.date.available | 2020-09-23T08:35:38Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 1052-3057 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/514635 | - |
dc.description.abstract | Background: Concomitant asymptomatic striatocapsular slit-like hemorrhage (SSH) is occasionally found in patients of spontaneous intracerebral hemorrhage (ICH), but was seldomly described in the literature. In this study, we described the clinico-radiological features of asymptomatic SSH in ICH patients with hypertensive microangiopathy. Methods and Results: 246 patients with strictly deep or mixed deep and lobar ICH/microbleeds were included. SSH was defined as hypointense lesions involving the lateral aspect of lentiform nucleus or external capsule in slit shape (>1.5 cm) on susceptibility-weighted imaging without history of associated symptoms. Demographics and neuroimaging markers were compared between patients with SSH and those without. Patients with SSH (n=24, 10%) and without SSH had comparable age (62.0 ± 12.6 vs. 62.3 ± 13.5, p = 0.912) and vascular risk factor profiles including the diagnosis of chronic hypertension, diabetes, and dyslipidemia (all p>0.05). SSH was associated with more common lobar microbleeds (79.2% vs 48.2%, p = 0.005), lacunes (75% vs. 41.4%, p = 0.002) and higher white matter hyperintensity (WMH) volumes (24.1 [10.4–46.3] vs. 13.9 [7.0–24.8] mL, p = 0.012) on MRI, as well as more frequent left ventricular hypertrophy (LVH) (50.0% vs. 20.5%, p = 0.004) and albuminuria (41.7% vs. 19.4%, p = 0.018). In multivariable analyses, SSH remains independently associated with LVH (p = 0.017) and albuminuria (p = 0.032) after adjustment for age, sex, microbleed, lacune and WMH volume. Conclusions: Asymptomatic SSH is associated with more severe cerebral small vessel disease-related change on brain MRI, and hypertensive cardiac and renal injury, suggesting a more advanced stage of chronic hypertension. ? 2020 Elsevier Inc. | - |
dc.relation.ispartof | Journal of Stroke and Cerebrovascular Diseases | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; albuminuria; Article; asymptomatic disease; brain hemorrhage; brain size; chronic disease; controlled study; cross-sectional study; disease severity; dyslipidemia; external capsule; female; heart left ventricle hypertrophy; human; hypertension; major clinical study; male; middle aged; neuroimaging; priority journal; striatocapsular slit like hemorrhage; susceptibility weighted imaging; aged; asymptomatic disease; brain hemorrhage; cerebrovascular disease; complication; corpus striatum; diagnostic imaging; diffusion weighted imaging; hypertension; predictive value; prognosis; register; risk factor; severity of illness index; Aged; Asymptomatic Diseases; Cerebral Small Vessel Diseases; Corpus Striatum; Cross-Sectional Studies; Diffusion Magnetic Resonance Imaging; External Capsule; Female; Humans; Hypertension; Intracranial Hemorrhage, Hypertensive; Male; Middle Aged; Predictive Value of Tests; Prognosis; Registries; Risk Factors; Severity of Illness Index | - |
dc.title | Asymptomatic Striatocapsular slit-like Hemorrhage as a Severity Marker in Patients with Hypertensive Angiopathy | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.jstrokecerebrovasdis.2020.105153 | - |
dc.identifier.pmid | 32912549 | - |
dc.identifier.scopus | 2-s2.0-85088647668 | - |
dc.relation.pages | 105153 | - |
dc.relation.journalvolume | 29 | - |
dc.relation.journalissue | 10 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Medical Imaging-NTUH | - |
crisitem.author.dept | Neurology-NTUH | - |
crisitem.author.dept | Neurology | - |
crisitem.author.dept | The Clinical Center for Neuroscience and Behavior | - |
crisitem.author.dept | Neurology-NTUH | - |
crisitem.author.dept | Neurology | - |
crisitem.author.dept | Neurology-NTUH | - |
crisitem.author.dept | Neurology | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Medical Imaging-NTUH | - |
crisitem.author.orcid | 0000-0002-1443-928X | - |
crisitem.author.orcid | 0000-0001-8420-6951 | - |
crisitem.author.orcid | 0000-0003-3731-5973 | - |
crisitem.author.orcid | 0000-0002-1456-3686 | - |
crisitem.author.orcid | 0000-0003-2995-9189 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
Appears in Collections: | 醫學院附設醫院 (臺大醫院) |
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