Viral coinfection replaces effects of suilysin on streptococcus suis adherence to and invasion of respiratory epithelial cells grown under air-liquid interface conditions
Journal
Infection and Immunity
Journal Volume
87
Journal Issue
8
Date Issued
2019
Author(s)
Meng, F.
Tong, J.
V?tsch, D.
Peng, J.-Y.
Cai, X.
Willenborg, M.
Herrler, G.
Valentin-Weigand, P.
Abstract
Streptococcus suis is an important zoonotic pathogen which can infect humans and pigs worldwide, posing a potential risk to global public health. Suilysin, a pore-forming cholesterol-dependent cytolysin, is considered to play an important role in the pathogenesis of S. suis infections. It is known that infection with influenza A viruses may favor susceptibility to secondary bacterial infection, resulting in more severe disease and increased mortality.
SDGs
Type
journal article