|Title:||Methods and compositions for unsilencing imprinted genes||Authors:||Philpot, Benjamin David
Zylka, Mark John
Roth, Bryan Lao
Allen, John Arthur
The present invention provides methods and compositions for inducing expression of Ubeza in a cell by contacting the cell with a topoisomerase inhibitor. Particular embodiments include a method of treating a genomic imprinting disorder, such as Angelman syndrome, in a subject by administering to the subject an effective amount of a topoisomerase inhibitor.
|Appears in Collections:||腦與心智科學研究所|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.