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  4. The metabolic syndrome increases cardiovascular mortality in Taiwanese elderly
 
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The metabolic syndrome increases cardiovascular mortality in Taiwanese elderly

Journal
European Journal of Clinical Investigation
Journal Volume
38
Journal Issue
7
Pages
469-475
Date Issued
2008
Author(s)
Chiung-Jung Wen  
Lee Y.S.
Lin W.Y.
HSIEN-LIANG HUANG  
CHIEN-AN YAO  
Sung P.K.
KUO-CHIN HUANG  
DOI
10.1111/j.1365-2362.2008.01965.x
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-45149114556&doi=10.1111%2fj.1365-2362.2008.01965.x&partnerID=40&md5=5fdff0f5c1699b74e90c526d00e8a0b7
https://scholars.lib.ntu.edu.tw/handle/123456789/517905
Abstract
Background: The prevalence of the metabolic syndrome (MetS) is high among the elderly. However, evidence that mortality increases with MetS is rare. In this study, we investigated the relationship between MetS, cardiovascular disease (CVD) and all cause mortality in the elderly. Materials and methods: A total 10 547 participants, aged 65 years and older, of baseline cohort were recruited from four nationwide Health Screening Centres in Taiwan from 1998 to 1999. The metabolic syndrome was defined according to the America Heart Association/National Heart Lung Blood Institute definition. Cox proportional hazards regression analyses were used to estimate the relative risks (RRs) of CVD and all cause mortality for those with MetS for up to 8 years of follow-up. Results: The baseline prevalence of MetS was 50.1% (45.6% in men and 54.4% in women, respectively). A total of 1312 participants died; of these, 300 participants died from CVD. Adjusted for age, gender, smoking, total cholesterol and estimated glomerular filtration rate, the RRs for CVD and all cause mortality among participants with MetS were 1.48 (95% confidence interval = 1.16-1.90) and 1.16 (1.03-1.30), respectively, for participants compared to those without MetS. The mean RRs for CVD, however, ranged from 1.21 to 5.31 among different combinations of MetS components. Conclusion: The elderly with MetS, compared to those without MetS, had a higher CVD and all cause mortality in Taiwan. Furthermore, different combinations of MetS components posed different risks to the mortality, which deserves further research in the future. ? 2008 The Authors.
SDGs

[SDGs]SDG3

Other Subjects
cholesterol; aged; article; cardiovascular disease; cause of death; cholesterol blood level; cohort analysis; confidence interval; controlled study; disease association; female; follow up; glomerulus filtration rate; health care organization; human; major clinical study; male; mass screening; medical research; metabolic syndrome X; mortality; prevalence; priority journal; proportional hazards model; risk factor; smoking; Taiwan; Aged; Aged, 80 and over; Asian Continental Ancestry Group; Cardiovascular Diseases; Epidemiologic Methods; Female; Humans; Male; Metabolic Syndrome X; Taiwan; Time Factors
Type
journal article

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To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

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開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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