https://scholars.lib.ntu.edu.tw/handle/123456789/517998
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Hwu H.-G. | en_US |
dc.contributor.author | Chen C.-H. | en_US |
dc.contributor.author | TZUNG-JENG HWANG | en_US |
dc.contributor.author | Liu C.-M. | en_US |
dc.contributor.author | Cheng J.J. | en_US |
dc.contributor.author | Lin S.-K. | en_US |
dc.contributor.author | Liu S.-K. | en_US |
dc.contributor.author | Chen C.-H. | en_US |
dc.contributor.author | Chi Y.-Y. | en_US |
dc.contributor.author | Ou-Young C.-W. | en_US |
dc.contributor.author | Lin H.-N. | en_US |
dc.contributor.author | WEI J. CHEN | en_US |
dc.creator | Hwu H.-G.;Chen C.-H.;Tzung-Jeng Hwang;Liu C.-M.;Cheng J.J.;Lin S.-K.;Liu S.-K.;Chen C.-H.;Chi Y.-Y.;Ou-Young C.-W.;Lin H.-N.;Chen W.J. | - |
dc.date.accessioned | 2020-10-23T11:55:10Z | - |
dc.date.available | 2020-10-23T11:55:10Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 0920-9964 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036641258&doi=10.1016%2fS0920-9964%2801%2900251-1&partnerID=40&md5=d77c2ede4ba8be2d2226114ea124b87e | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/517998 | - |
dc.description.abstract | This study subgroups schizophrenic patients based on symptoms assessed on admission and examines the validity of the subgrouping using follow-up data and other clinical outcome variables. Schizophrenic patients (n=163) from consecutive admission received ratings on the positive and negative syndrome scale (PANSS) on admission and during a 1-year follow-up course. An exploratory graphic analysis on the admission PANSS derived four symptom dimensions: negative symptoms, disorganized thought, hostility/excitement and delusions/hallucinations. This yielded two subgroups of patients on admission, a group with marked negative (GWNEG) and a group without marked negative (GONEG) symptoms. Compared with the GONEG, the GWNEG had a poorer recovery rate, more impairment in attention, a slower response of the delusion/hallucination symptoms to neuroleptic treatment and a longer duration of index hospitalization. At a one-year follow-up, the GWNEG assessed on admission had persistently higher scores on the negative symptom and disorganized thought syndromes, less relapse rate, a shorter duration on job, as well as worse social functioning than the GONEG. Thus, the GONEG might comprise patients having a pure paranoid syndrome with quick and better treatment response, while the GWNEG comprises patients with the blunt-disorganization syndrome having a poorer outcome. ? 2002 Elsevier Science B.V. All rights reserved. | - |
dc.relation.ispartof | Schizophrenia Research | - |
dc.subject | Follow-up; Generalized association plots; Schizophrenia subtypes; Symptom dimensions; Validity | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | chlorpromazine; trihexyphenidyl; adult; article; clinical feature; controlled study; delusion; disease severity; disorientation; female; follow up; hallucination; hospital admission; hostility; human; job performance; length of stay; major clinical study; male; negative syndrome; outcomes research; priority journal; rating scale; relapse; schizophrenia; social status; symptom; validation process; Adult; Depression; Female; Follow-Up Studies; Humans; Male; Middle Aged; Patient Admission; Prospective Studies; Psychiatric Status Rating Scales; Psychometrics; Schizophrenia; Schizophrenic Psychology | - |
dc.title | Symptom patterns and subgrouping of schizophrenic patients: Significance of negative symptoms assessed on admission | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/S0920-9964(01)00251-1 | - |
dc.identifier.pmid | 12084425 | - |
dc.identifier.scopus | 2-s2.0-0036641258 | - |
dc.relation.pages | 105-119 | - |
dc.relation.journalvolume | 56 | - |
dc.relation.journalissue | 1-2 | - |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.dept | Neurobiology and Cognitive Science Center | - |
crisitem.author.dept | Center for Integrated Dementia Care | - |
crisitem.author.dept | Epidemiology and Preventive Medicine | - |
crisitem.author.dept | Public Health | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.orcid | 0000-0001-7894-9484 | - |
crisitem.author.orcid | 0000-0001-5899-5870 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | Others: University-Level Research Centers | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫療器材與醫學影像研究所 |
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