https://scholars.lib.ntu.edu.tw/handle/123456789/518345
Title: | Immunohistochemical localization of deoxyribonuclease I in rat parotid gland | Authors: | PEI-JEN LOU Chen W.-P Liao T.-H. |
Keywords: | Deoxyribonuclease I; Immunohistochemistry; Parotid gland | Issue Date: | 1997 | Journal Volume: | 32 | Journal Issue: | 6 | Start page/Pages: | 620-626 | Source: | Journal of the Otolaryngological Society of the Republic of China | Abstract: | Background: Deoxyribonuclease (DNase) is one of the digestive enzymes secreted by the parotid gland. Recent progresses in molecular biology and biochemistry have enabled us to learn more about the function of DNase in cells. In addition to its well-known digestive function, DNase was found to be closely related to some cancers and apoptosis. Methods: We use immunohistochemical techniques with purified antibody to study the distribution of DNase I in rat pancreas and parotid gland. Results: Rat DNase I is localized in secretary ganules of parotid gland but not found in pancreaS. Conclusions: Our results suggest that the role in digestive function of parotid gland may differ among different species and localization of DNase I may help us to the further study of parotid gland in cell biology. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031408446&partnerID=40&md5=d73bce5f538aad7cf119a32641094aa9 https://scholars.lib.ntu.edu.tw/handle/123456789/518345 |
ISSN: | 1019-6102 | SDG/Keyword: | deoxyribonuclease i; animal tissue; apoptosis; article; enzyme localization; enzyme release; nonhuman; pancreas; parotid gland; rat; secretory granule |
Appears in Collections: | 醫學系 |
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