https://scholars.lib.ntu.edu.tw/handle/123456789/521340
標題: | Applicability of staging systems for patients with hepatocellular carcinoma is dependent on treatment method - Analysis of 2010 Taiwanese patients | 作者: | CHIEN-HUNG CHEN Hu F.-C. GUAN-TARN HUANG PO-HUANG LEE Tsang Y.-M. ANN-LII CHENG DING-SHINN CHEN Wang J.-D. JIN-CHUAN SHEU |
公開日期: | 2009 | 卷: | 45 | 期: | 9 | 起(迄)頁: | 1630-1639 | 來源出版物: | European Journal of Cancer | 摘要: | The aim of this study was to compare six prognostic staging systems (Okuda stage, TNM stage, CLIP score, BCLC stage, JIS score and Tokyo score) in predicting survival in patients with hepatocellular carcinoma (HCC). A total of 2010 Taiwanese HCC patients were included. Demographic, laboratory and tumour characteristics were determined at diagnosis. Predictors of survival included serum levels of albumin, total bilirubin, alkaline phosphatase, α-fetoprotein, ascites, tumour size and portal vein invasion. The Tokyo score was the most informative one for predicting the survival of HCC patients as a whole, receiving surgical resection, or receiving transarterial chemoembolisation. CLIP score was the best fit system for HCC patients receiving chemotherapy or supportive care. Each staging system showed a significant difference in predicting the probability of survival across different stages. The applicability of staging systems for patients with HCC was dependent on treatment methods. ? 2008 Elsevier Ltd. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-67349206740&doi=10.1016%2fj.ejca.2008.12.025&partnerID=40&md5=93b8119ae8b2b21ee0d911ff96dbd7ee https://scholars.lib.ntu.edu.tw/handle/123456789/521340 |
ISSN: | 0959-8049 | DOI: | 10.1016/j.ejca.2008.12.025 | SDG/關鍵字: | albumin; alkaline phosphatase; alpha fetoprotein; antineoplastic agent; bilirubin; adult; aged; article; ascites; cancer chemotherapy; cancer staging; cancer survival; cancer therapy; chemoembolization; controlled study; disease marker; female; histopathology; human; human tissue; laboratory test; liver cell carcinoma; major clinical study; male; metastasis; portal vein thrombosis; priority journal; prognosis; protein blood level; scoring system; Taiwan; tumor volume; Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Analysis; Tumor Markers, Biological |
顯示於: | 醫學系 |
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