https://scholars.lib.ntu.edu.tw/handle/123456789/521445
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | MENG-KUN TSAI | en_US |
dc.contributor.author | Wu M.-H. | en_US |
dc.contributor.author | SHYH-CHYI LO | en_US |
dc.contributor.author | I-RUE LAI | en_US |
dc.contributor.author | Yu S.-C. | en_US |
dc.contributor.author | RAY-HWANG YUAN | en_US |
dc.contributor.author | PO-HUANG LEE | en_US |
dc.date.accessioned | 2020-11-19T03:20:17Z | - |
dc.date.available | 2020-11-19T03:20:17Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0929-6646 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33749360087&doi=10.1016%2fS0929-6646%2809%2960208-4&partnerID=40&md5=1d23039e0a3b200be39df9ac20fb141a | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/521445 | - |
dc.description.abstract | The serious shortage of cadaveric organs has prompted the development of ABO-incompatible live donor renal transplantation. We report our experience of the initial two live donor ABO incompatible renal transplants at our hospital. The first patient was a 55-year-old type A female who received a kidney from her AB type husband. The second patient was a 27-year-old type O male who received renal transplantation from his type A father. Preconditioning immunosuppressive therapy in the two patients with tacrolimus, mycophenolate mofetil and methylprednisolone was started 7 days before transplantation. During the period of preconditioning, double filtration plasmapheresis (DFPP) was employed to remove anti-A and -B antibodies. Laparoscopic splenectomy and renal transplantation were performed after the anti-donor ABO antibodies were reduced to a titer of 1:4. Rituximab, a humanized monoclonal anti- CD20 antibody, was administered to the second patient due to a rebound in the anti-A antibody titer during the preconditioning period. Under a tacrolimus-based immunosuppressive regimen, both patients recovered very well without any evidence of rejection. Serum creatinine levels were 1.0 and 1.4 mg/dL at 6 and 3 months after transplantation, respectively. These cases illustrate that with new immunosuppressive agents, DFPP and splenectomy, ABO-incompatible renal transplantation can be successfully conducted in end-stage renal disease patients whose only available live donors are blood group incompatible. ? 2006 Elsevier & Formosan Medical Association. | - |
dc.publisher | Scientific Communications International Ltd | - |
dc.relation.ispartof | Journal of the Formosan Medical Association | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | creatinine; fresh frozen plasma; glucose; hemoglobin; methylprednisolone; mycophenolic acid 2 morpholinoethyl ester; nitrogen; prednisolone; rapamycin; rapaume; rituximab; tacrolimus; unclassified drug; urea; adult; antibody titer; article; blood cell count; blood clotting disorder; blood group AB; blood group ABO incompatibility; case report; chronic kidney failure; clinical feature; continuous infusion; creatinine blood level; dose response; drug dose reduction; drug substitution; epigastric pain; female; glucose blood level; hemoglobin determination; HLA system; human; immunological monitoring; immunosuppressive treatment; kidney transplantation; laboratory test; laparoscopic surgery; leukocyte count; liver function test; living donor; lymphocyte depletion; male; nephrectomy; physical examination; plasmapheresis; postoperative period; recipient; splenectomy; thrombocyte count; treatment outcome; urea nitrogen blood level; vomiting | - |
dc.title | Initial experience with ABO-incompatible live donor renal transplantation | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/S0929-6646(09)60208-4 | - |
dc.identifier.pmid | 16959628 | - |
dc.identifier.scopus | 2-s2.0-33749360087 | - |
dc.relation.pages | 775-779 | - |
dc.relation.journalvolume | 105 | - |
dc.relation.journalissue | 9 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | NTU Hsin-Chu Hospital | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Laboratory Medicine-NTUH | - |
crisitem.author.dept | Anatomy and Cell Biology | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | NTU BioMedical Park Hospital | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.orcid | 0000-0002-2962-8913 | - |
crisitem.author.orcid | 0000-0002-6745-5953 | - |
crisitem.author.orcid | 0000-0002-3444-8255 | - |
crisitem.author.orcid | 0000-0002-2767-633X | - |
crisitem.author.orcid | 0000-0001-5831-035X | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital Hsin-Chu Branch | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital Hsin-Chu Branch | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
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