https://scholars.lib.ntu.edu.tw/handle/123456789/521737
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Lee L.-T. | en_US |
dc.contributor.author | Huang H.-Y. | en_US |
dc.contributor.author | KUO-CHIN HUANG | en_US |
dc.contributor.author | Chen C.-Y. | en_US |
dc.contributor.author | WEN-CHUNG LEE | en_US |
dc.date.accessioned | 2020-11-19T08:19:09Z | - |
dc.date.available | 2020-11-19T08:19:09Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1047-2797 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-63749107802&doi=10.1016%2fj.annepidem.2008.12.013&partnerID=40&md5=536c256e129968928cf3c63f09c2bf9f | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/521737 | - |
dc.description.abstract | Purpose: Hepatocellular carcinoma (HCC) is one of the most common malignant primary liver tumors worldwide. A previous study showed a decline in pediatric HCC in Taiwan after the universal vaccination program was initiated in 1984. We investigated whether the recent change in HCC mortality in Taiwan represented a short-term fluctuation or an emerging long-term decline trend. Methods: An age-period-cohort analysis was conducted to show HCC mortality trends between 1976 and 2005. A total of 121,643 HCC mortality cases (92,926 males and 28,717 females) of individuals older than 40 years of age was used in the analyses. Results: Results indicate an increasing secular trend in HCC mortality over the last three decades in people aged 60 years and above. In the age group of >85 years old, the mortality rate for males and females was 7.47 (95% confidence interval [95% CI]: 6.24-8.94) and 25.0 (95% CI: 15.5-40.2) times greater than in the youngest age group (40-44), respectively. The relative risk of dying from HCC in the period 2001-2005 was 1.36 (95% CI: 1.23-1.50) for males compared to the 1976-1980 time period, and 1.42 (95% CI: 1.17-1.72) for females compared to the 1986-1990 time period. A strong birth-cohort effect was also found. Individuals born around 1936 had the highest risk of dying from HCC. Conclusion: These findings imply that important determinants of HCC may occur early in life, with their effects only becoming apparent much later. ? 2009 Elsevier Inc. All rights reserved. | - |
dc.language.iso | English | - |
dc.relation.ispartof | Annals of Epidemiology | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; aged; article; cancer mortality; controlled study; female; groups by age; human; liver cell carcinoma; major clinical study; male; priority journal; sex difference; Taiwan; Adult; Age Factors; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Cohort Studies; Female; Hepatitis B Vaccines; Humans; Liver Neoplasms; Male; Middle Aged; Mortality; Sex Factors; Taiwan | - |
dc.title | Age-Period-Cohort Analysis of Hepatocellular Carcinoma Mortality in Taiwan, 1976-2005 | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.annepidem.2008.12.013 | - |
dc.identifier.pmid | 19362276 | - |
dc.identifier.scopus | 2-s2.0-63749107802 | - |
dc.relation.pages | 323-328 | - |
dc.relation.journalvolume | 19 | - |
dc.relation.journalissue | 5 | - |
item.fulltext | no fulltext | - |
item.openairetype | journal article | - |
item.languageiso639-1 | English | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Family Medicine | - |
crisitem.author.dept | Family Medicine-NTUH | - |
crisitem.author.dept | Health Behaviors and Community Sciences | - |
crisitem.author.dept | Psychology | - |
crisitem.author.dept | Institute of Health Data Analytics and Statistics | - |
crisitem.author.dept | Public Health | - |
crisitem.author.orcid | 0000-0002-6029-5520 | - |
crisitem.author.orcid | 0000-0003-3171-7672 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Science | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Public Health | - |
顯示於: | 流行病學與預防醫學研究所 |
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