https://scholars.lib.ntu.edu.tw/handle/123456789/523428
DC 欄位 | 值 | 語言 |
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dc.contributor.author | Wong J.Y.Y. | en_US |
dc.contributor.author | Zhang H | en_US |
dc.contributor.author | Hsiung C.A. | en_US |
dc.contributor.author | Shiraishi K. | en_US |
dc.contributor.author | Yu K. | en_US |
dc.contributor.author | Matsuo K. | en_US |
dc.contributor.author | Wong M.P. | en_US |
dc.contributor.author | Hong Y.-C. | en_US |
dc.contributor.author | Wang J. | en_US |
dc.contributor.author | Seow W.J. | en_US |
dc.contributor.author | Wang Z. | en_US |
dc.contributor.author | Pang H. | en_US |
dc.contributor.author | Li Y. | en_US |
dc.contributor.author | Choi J.E. | en_US |
dc.contributor.author | Park K.H. | en_US |
dc.contributor.author | Sung S.W. | en_US |
dc.contributor.author | Liu L. | en_US |
dc.contributor.author | Kang C.H. | en_US |
dc.contributor.author | Zhu M. | en_US |
dc.contributor.author | Chen C.-H. | en_US |
dc.contributor.author | Yang T.-Y. | en_US |
dc.contributor.author | Song M. | en_US |
dc.contributor.author | Xu J. | en_US |
dc.contributor.author | Guan P. | en_US |
dc.contributor.author | Tan W. | en_US |
dc.contributor.author | Wang C.-L. | en_US |
dc.contributor.author | Hsin M. | en_US |
dc.contributor.author | Sit K.-Y. | en_US |
dc.contributor.author | Ho J. | en_US |
dc.contributor.author | Chen Y. | en_US |
dc.contributor.author | Choi Y.Y. | en_US |
dc.contributor.author | Hung J.-Y. | en_US |
dc.contributor.author | Kim H.N. | en_US |
dc.contributor.author | Kim J.S. | en_US |
dc.contributor.author | Yoon H.I. | en_US |
dc.contributor.author | Lin C.-C. | en_US |
dc.contributor.author | Park I.K. | en_US |
dc.contributor.author | Xu P. | en_US |
dc.contributor.author | Wang Y. | en_US |
dc.contributor.author | He Q. | en_US |
dc.contributor.author | Perng R.-P. | en_US |
dc.contributor.author | Chen C.-Y. | en_US |
dc.contributor.author | Vermeulen R. | en_US |
dc.contributor.author | Chang I.-S. | en_US |
dc.contributor.author | Wu J. | en_US |
dc.contributor.author | Lim W.-Y. | en_US |
dc.contributor.author | Chen K.-C. | en_US |
dc.contributor.author | Li Y.-J. | en_US |
dc.contributor.author | Li J. | en_US |
dc.contributor.author | Chen H. | en_US |
dc.contributor.author | CHONG-JEN YU | en_US |
dc.contributor.author | Jin L. | en_US |
dc.contributor.author | Chen T.-Y. | en_US |
dc.contributor.author | Jiang S.-S. | en_US |
dc.contributor.author | Chatterjee N. | en_US |
dc.contributor.author | Liu J. | en_US |
dc.contributor.author | Yamaji T. | en_US |
dc.contributor.author | Hicks B. | en_US |
dc.contributor.author | Wyatt K. | en_US |
dc.contributor.author | Li S.A. | en_US |
dc.contributor.author | Dai J. | en_US |
dc.contributor.author | Ma H. | en_US |
dc.contributor.author | Jin G. | en_US |
dc.contributor.author | Song B. | en_US |
dc.contributor.author | Wang Z. | en_US |
dc.contributor.author | Hu W. | en_US |
dc.contributor.author | Cheng S. | en_US |
dc.contributor.author | Li X. | en_US |
dc.contributor.author | Ren Y. | en_US |
dc.contributor.author | Cui P. | en_US |
dc.contributor.author | Iwasaki M. | en_US |
dc.contributor.author | Shimazu T. | en_US |
dc.contributor.author | Tsugane S. | en_US |
dc.contributor.author | Zhu J. | en_US |
dc.contributor.author | Yang K. | en_US |
dc.contributor.author | Jiang G. | en_US |
dc.contributor.author | Wu C. | en_US |
dc.contributor.author | Fei K. | en_US |
dc.contributor.author | Wu G. | en_US |
dc.contributor.author | Lin H.-C. | en_US |
dc.contributor.author | Chen H.-L. | en_US |
dc.contributor.author | Fang Y.-H. | en_US |
dc.contributor.author | Tsai F.-Y. | en_US |
dc.contributor.author | Hsieh W.-S. | en_US |
dc.contributor.author | Yu J. | en_US |
dc.contributor.author | Stevens V.L. | en_US |
dc.contributor.author | Laird-Offringa I.A. | en_US |
dc.contributor.author | Mitsudomi T. | en_US |
dc.contributor.author | Marconett C.N. | en_US |
dc.contributor.author | Rieswijk L. | en_US |
dc.contributor.author | Chao A. | en_US |
dc.contributor.author | PAN-CHYR YANG | en_US |
dc.contributor.author | Shu X.-O. | en_US |
dc.contributor.author | Wu T. | en_US |
dc.contributor.author | Wu Y.L. | en_US |
dc.contributor.author | Lin D. | en_US |
dc.contributor.author | Chen K. | en_US |
dc.contributor.author | Zhou B. | en_US |
dc.contributor.author | Zheng W. | en_US |
dc.contributor.author | Huang Y.-C. | en_US |
dc.contributor.author | Kohno T. | en_US |
dc.contributor.author | Shen H. | en_US |
dc.contributor.author | Chanock S.J. | en_US |
dc.contributor.author | Rothman N. | en_US |
dc.contributor.author | Lan Q. | en_US |
dc.contributor.author | Kim J.H. | en_US |
dc.contributor.author | Seow A. | en_US |
dc.contributor.author | Caporaso N.E. | en_US |
dc.contributor.author | Shin M.-H. | en_US |
dc.contributor.author | Chung L.P. | en_US |
dc.contributor.author | An S.-J. | en_US |
dc.contributor.author | Wang P. | en_US |
dc.contributor.author | Yang Y. | en_US |
dc.contributor.author | Zheng H. | en_US |
dc.contributor.author | Yatabe Y. | en_US |
dc.contributor.author | Zhang X.-C. | en_US |
dc.contributor.author | Kim Y.T. | en_US |
dc.contributor.author | Cai Q. | en_US |
dc.contributor.author | Yin Z. | en_US |
dc.contributor.author | Kim Y.-C. | en_US |
dc.contributor.author | Bassig B.A. | en_US |
dc.contributor.author | Chang J. | en_US |
dc.contributor.author | Ho J.C.M. | en_US |
dc.contributor.author | Ji B.-T. | en_US |
dc.contributor.author | Daigo Y. | en_US |
dc.contributor.author | Ito H. | en_US |
dc.contributor.author | Momozawa Y. | en_US |
dc.contributor.author | Ashikawa K. | en_US |
dc.contributor.author | Kamatani Y. | en_US |
dc.contributor.author | Honda T. | en_US |
dc.contributor.author | Hosgood H.D. | en_US |
dc.contributor.author | Sakamoto H. | en_US |
dc.contributor.author | Kunitoh H. | en_US |
dc.contributor.author | Tsuta K. | en_US |
dc.contributor.author | Watanabe S.-I. | en_US |
dc.contributor.author | Kubo M. | en_US |
dc.contributor.author | Miyagi Y. | en_US |
dc.contributor.author | Nakayama H. | en_US |
dc.contributor.author | Matsumoto S. | en_US |
dc.contributor.author | Tsuboi M. | en_US |
dc.contributor.author | Goto K. | en_US |
dc.contributor.author | Shi J. | en_US |
dc.contributor.author | Song L. | en_US |
dc.contributor.author | Hua X. | en_US |
dc.contributor.author | Takahashi A. | en_US |
dc.contributor.author | Goto A. | en_US |
dc.contributor.author | Minamiya Y. | en_US |
dc.contributor.author | Shimizu K. | en_US |
dc.contributor.author | Tanaka K. | en_US |
dc.contributor.author | Wei F. | en_US |
dc.contributor.author | Matsuda F. | en_US |
dc.contributor.author | Su J. | en_US |
dc.contributor.author | Kim Y.H. | en_US |
dc.contributor.author | Oh I.-J. | en_US |
dc.contributor.author | Song F. | en_US |
dc.contributor.author | Su W.-C. | en_US |
dc.contributor.author | Chen Y.-M. | en_US |
dc.contributor.author | Chang G.-C. | en_US |
dc.contributor.author | KUAN-YU CHEN | en_US |
dc.contributor.author | Huang M.-S. | en_US |
dc.contributor.author | Chien L.-H. | en_US |
dc.contributor.author | Xiang Y.-B. | en_US |
dc.contributor.author | Park J.Y. | en_US |
dc.contributor.author | Kweon S.-S. | en_US |
dc.contributor.author | Chen C.-J. | en_US |
dc.contributor.author | Lee K.-M. | en_US |
dc.contributor.author | Blechter B. | en_US |
dc.contributor.author | Li H. | en_US |
dc.contributor.author | Gao Y.-T. | en_US |
dc.contributor.author | Qian B. | en_US |
dc.contributor.author | Lu D. | en_US |
dc.contributor.author | Liu J. | en_US |
dc.contributor.author | Jeon H.-S. | en_US |
dc.contributor.author | Hsiao C.-F. | en_US |
dc.contributor.author | Sung J.S. | en_US |
dc.contributor.author | Tsai Y.-H. | en_US |
dc.contributor.author | Jung Y.J. | en_US |
dc.contributor.author | Guo H. | en_US |
dc.contributor.author | Hu Z. | en_US |
dc.contributor.author | Wang W.-C. | en_US |
dc.contributor.author | Chung C.C. | en_US |
dc.contributor.author | Burdett L. | en_US |
dc.contributor.author | Yeager M. | en_US |
dc.contributor.author | Hutchinson A. | en_US |
dc.contributor.author | Berndt S.I. | en_US |
dc.contributor.author | Wu W. | en_US |
dc.creator | Wong J.Y.Y.; Zhang H.; Hsiung C.A.; Shiraishi K.; Yu K.; Matsuo K.; Wong M.P.; Hong Y.-C.; Wang J.; Seow W.J.; Wang Z.; Song M.; Kim H.N.; Chang I.-S.; Chatterjee N.; Hu W.; Wu C.; Mitsudomi T.; Zheng W.; Kim J.H.; Seow A.; Caporaso N.E.; Shin M.-H.; Chung L.P.; An S.-J.; Wang P.; Yang Y.; Zheng H.; Yatabe Y.; Zhang X.-C.; Kim Y.T.; Cai Q.; Yin Z.; Kim Y.-C.; Bassig B.A.; Chang J.; Ho J.C.M.; Ji B.-T.; Daigo Y.; Ito H.; Momozawa Y.; Ashikawa K.; Kamatani Y.; Honda T.; Hosgood H.D.; Sakamoto H.; Kunitoh H.; Tsuta K.; Watanabe S.-I.; Kubo M.; Miyagi Y.; Nakayama H.; Matsumoto S.; Tsuboi M.; Goto K.; Shi J.; Song L.; Hua X.; Takahashi A.; Goto A.; Minamiya Y.; Shimizu K.; Tanaka K.; Wei F.; Matsuda F.; Su J.; Kim Y.H.; Oh I.-J.; Song F.; Su W.-C.; Chen Y.-M.; Chang G.-C.; Chen K.-Y.; Huang M.-S.; Chien L.-H.; Xiang Y.-B.; Park J.Y.; Kweon S.-S.; Chen C.-J.; Lee K.-M.; Blechter B.; Li H.; Gao Y.-T.; Qian B.; Lu D.; Liu J.; Jeon H.-S.; Hsiao C.-F.; Sung J.S.; Tsai Y.-H.; Jung Y.J.; Guo H.; Hu Z.; Wang W.-C.; Chung C.C.; Burdett L.; Yeager M.; Hutchinson A.; Berndt S.I.; Wu W.; Pang H.; Li Y.; Choi J.E.; Park K.H.; Sung S.W.; Liu L.; Kang C.H.; Zhu M.; Chen C.-H.; Yang T.-Y.; Xu J.; Guan P.; Tan W.; Wang C.-L.; Hsin M.; Sit K.-Y.; Ho J.; Chen Y.; Choi Y.Y.; Hung J.-Y.; Kim J.S.; Yoon H.I.; Lin C.-C.; Park I.K.; Xu P.; Wang Y.; He Q.; Perng R.-P.; Chen C.-Y.; Vermeulen R.; Wu J.; Lim W.-Y.; Chen K.-C.; Li Y.-J.; Li J.; Chen H.; Yu C.-J.; Jin L.; Chen T.-Y.; Jiang S.-S.; Liu J.; Yamaji T.; Hicks B.; Wyatt K.; Li S.A.; Dai J.; Ma H.; Jin G.; Song B.; Wang Z.; Cheng S.; Li X.; Ren Y.; Cui P.; Iwasaki M.; Shimazu T.; Tsugane S.; Zhu J.; Yang K.; Jiang G.; Fei K.; Wu G.; Lin H.-C.; Chen H.-L.; Fang Y.-H.; Tsai F.-Y.; Hsieh W.-S.; Yu J.; Stevens V.L.; Laird-Offringa I.A.; Marconett C.N.; Rieswijk L.; Chao A.; Pan-Chyr Yang; Shu X.-O.; Wu T.; Wu Y.L.; Lin D.; Chen K.; Zhou B.; Huang Y.-C.; Kohno T.; Shen H.; Chanock S.J.; Rothman N.; Lan Q. | - |
dc.date.accessioned | 2020-12-02T02:33:05Z | - |
dc.date.available | 2020-12-02T02:33:05Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 0888-7543 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068966697&doi=10.1016%2fj.ygeno.2019.07.008&partnerID=40&md5=2f03da81363ca97dba6e57d733f19b1b | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/523428 | - |
dc.description.abstract | We investigated whether genetic susceptibility to tuberculosis (TB) influences lung adenocarcinoma development among never-smokers using TB genome-wide association study (GWAS) results within the Female Lung Cancer Consortium in Asia. Pathway analysis with the adaptive rank truncated product method was used to assess the association between a TB-related gene-set and lung adenocarcinoma using GWAS data from 5512 lung adenocarcinoma cases and 6277 controls. The gene-set consisted of 31 genes containing known/suggestive associations with genetic variants from previous TB-GWAS. Subsequently, we followed-up with Mendelian Randomization to evaluate the association between TB and lung adenocarcinoma using three genome-wide significant variants from previous TB-GWAS in East Asians. The TB-related gene-set was associated with lung adenocarcinoma (p = 0.016). Additionally, the Mendelian Randomization showed an association between TB and lung adenocarcinoma (OR = 1.31, 95% CI: 1.03, 1.66, p = 0.027). Our findings support TB as a causal risk factor for lung cancer development among never-smoking Asian women. ? 2019 | en_US |
dc.publisher | Academic Press Inc. | en_US |
dc.relation.ispartof | Genomics | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | HLA DQA1 antigen; adult; Article; controlled study; DLG2 gene; East Asian; female; FHAD1 gene; gene; genetic association; genetic susceptibility; genetic variability; genome-wide association study; HLA DQA1 gene; human; LRRC69 gene; lung adenocarcinoma; major clinical study; MEIS2 gene; Mendelian randomization analysis; never smoker; observational study; pathway analysis; priority journal; single nucleotide polymorphism; statistical analysis; tuberculosis; ZFPM2 gene; Asian continental ancestry group; genetics; lung adenocarcinoma; lung tuberculosis; lung tumor; Adenocarcinoma of Lung; Asian Continental Ancestry Group; Female; Genome-Wide Association Study; Humans; Lung Neoplasms; Mendelian Randomization Analysis; Non-Smokers; Tuberculosis, Pulmonary | - |
dc.title | Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.ygeno.2019.07.008 | - |
dc.identifier.pmid | 31306748 | - |
dc.identifier.scopus | 2-s2.0-85068966697 | - |
dc.relation.pages | 1223-1232 | en_US |
dc.relation.journalvolume | 112 | en_US |
dc.relation.journalissue | 2 | en_US |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | National Taiwan University Hospital Hsin-Chu Branch | - |
crisitem.author.dept | NTU BioMedical Park Hospital | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Clinical Medicine | - |
crisitem.author.dept | Clinical Pharmacy | - |
crisitem.author.dept | Oncology | - |
crisitem.author.dept | Biomedical Electronics and Bioinformatics | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-5664-9392 | - |
crisitem.author.orcid | 0000-0001-6330-6048 | - |
crisitem.author.orcid | 0000-0002-5639-9773 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital Hsin-Chu Branch | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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