https://scholars.lib.ntu.edu.tw/handle/123456789/524318
Title: | High-density lipoprotein-cholesterol trajectory pattern, associated lifestyle and biochemical factors among Taiwanese | Authors: | Lee Y.-C. KUO-LIONG CHIEN BAI-CHIN LEE HUNG-JU LIN Hsu H.-C. MING-FONG CHEN |
Issue Date: | 2009 | Journal Volume: | 73 | Journal Issue: | 10 | Start page/Pages: | 1887-1892 | Source: | Circulation Journal | Abstract: | Background: Little is known about high-density lipoprotein-cholesterol (HDL-C) trajectory patterns among ethnic Chinese in Taiwan, or the effects of lifestyle and biochemical measurements on these trajectory patterns. Methods and Results: This longitudinal study was based on 330 adult participants who underwent biochemical measurements annually from 2003 to 2006. As time progressed, HDL-C increased significantly; women had a consistently higher value (10mg/dl) than men. An increase of 1 kg/m2 in body mass index was associated with -1.00±0.25 mg/dl HDL-C for women (P=0.0001) and -0.78±0.11 mg/dl for men (P<0.0001). Current smoking was inversely associated with HDL-C in men only. Systolic blood pressure and exercisefrequency were positively associated with HDL-C in men only. Compared with non-smokers, participants who smoked had a lower HDL-C level of -8.42±4.90mg/dl in women (P=0.09) and -3.60±0.94mg/dl in men (P=0.0001). In contrast, a 1-h increase in exercise frequency every week was related to an increased HDL-C level of 0.38±0.28mg/dl for women (P=0.18) and 0.53±0.14mg/dl for men (P=0.0001). Conclusions: An increase in HDL-C was shown over a 4-year period and gender-specific lifestyle factors were associated with HDL-C concentration among ethnic Chinese in Taiwan. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-70349859856&doi=10.1253%2fcircj.CJ-09-0209&partnerID=40&md5=9c16b2a1d7e4b3d328d58b08d3865880 https://scholars.lib.ntu.edu.tw/handle/123456789/524318 |
ISSN: | 1346-9843 | DOI: | 10.1253/circj.CJ-09-0209 | SDG/Keyword: | high density lipoprotein cholesterol; low density lipoprotein cholesterol; triacylglycerol; adult; article; body mass; Chinese; cholesterol blood level; exercise; female; human; inflammation; lifestyle; major clinical study; male; obesity; smoking; systolic blood pressure; Taiwan; Age Factors; Asian Continental Ancestry Group; Biological Markers; Blood Pressure; Body Mass Index; China; Cholesterol, HDL; Dyslipidemias; Exercise; Female; Humans; Life Style; Longitudinal Studies; Male; Middle Aged; Risk Factors; Sex Factors; Smoking; Taiwan; Time Factors |
Appears in Collections: | 醫學系 |
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