https://scholars.lib.ntu.edu.tw/handle/123456789/524381
標題: | CMR-derived ECVs vary with myocardial region and associate with the regional wall thickness | 作者: | MAO-YUAN SU Hou, Kuei-Yuan Liu, Ming-Hung Lin, Tien-Min JYH-MING JIMMY JUANG LIAN-YU LIN CHO-KAI WU HSI-YU YU Yang, Shun-Chung YU-SEN HUANG Niisato, Emi YEUN-CHUNG CHANG |
公開日期: | 1-十二月-2020 | 卷: | 10 | 期: | 1 | 來源出版物: | Scientific reports | 摘要: | This study was designed to identify whether the position and size of the region of interest (ROI) influence extracellular volume fraction (ECV) measurements. Patients with localized (n = 203) or infiltrative (n = 215) cardiomyopathies and 36 normal controls were enrolled in this study. ECV measurements at 4 different regions, including the anterior, septal, posterior and lateral wall regions, were measured, and all groups were compared. Regional ECV was correlated with the corresponding regional wall thickness. The diagnostic power to differentiate the myocardial abnormalities was evaluated for each myocardial region. ECVs measured using five different ROI sizes within each myocardial region were compared. Our results showed that ECVs varied among the myocardial regions, and this variation was significantly associated with regional wall thicknesses. For the detection of myocardial abnormalities, regional ECV revealed similar results as ECV derived from the whole region except for the anterior region. No significant difference was found in the ECVs measured using the five different ROI sizes. In conclusion, CMR-derived ECVs vary with myocardial region, and this variation is significantly associated with the regional wall thickness. In contrast, the measured size of the ROI has less of an effect on the ECV. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/524381 | ISSN: | 2045-2322 | DOI: | 10.1038/s41598-020-78043-5 |
顯示於: | 醫學系 |
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Sci Rep 2020.pdf | 1.99 MB | Adobe PDF | 檢視/開啟 |
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