https://scholars.lib.ntu.edu.tw/handle/123456789/524976
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Wang C.-Y. | en_US |
dc.contributor.author | Chang Y.-H. | en_US |
dc.contributor.author | LI-MIN HUANG | en_US |
dc.contributor.author | Chi H. | en_US |
dc.contributor.author | Chiu N.-C. | en_US |
dc.contributor.author | LUAN-YIN CHANG | en_US |
dc.contributor.author | CHUN-YI LU | en_US |
dc.contributor.author | Huang Y.-C. | en_US |
dc.contributor.author | Lin H.-C. | en_US |
dc.contributor.author | JIAN-TE LEE | en_US |
dc.contributor.author | Liu C.-C. | en_US |
dc.contributor.author | Huang Y.-C. | en_US |
dc.contributor.author | Ho Y.-H. | en_US |
dc.contributor.author | Tu Y.-H. | en_US |
dc.contributor.author | Wang J.-Y. | en_US |
dc.contributor.author | Huang D.T.-N. | en_US |
dc.contributor.author | Taiwan Pediatric Infectious Disease Alliance | en_US |
dc.date.accessioned | 2020-12-08T06:21:44Z | - |
dc.date.available | 2020-12-08T06:21:44Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1684-1182 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85075460048&doi=10.1016%2fj.jmii.2019.09.010&partnerID=40&md5=ae6f51ff215459b116da7459b1212285 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/524976 | - |
dc.description.abstract | Background: Influenza is a major cause of acute respiratory infection burden worldwide, leading to many hospitalizations. An annual influenza vaccine is believed to be the best way to prevent influenza-related illnesses. We focused on the efficacies of other possible preventive measures such as increasing sun exposure time and dietary supplements to prevent these illnesses. Methods: We conducted a matched-pair case–control study along with the Taiwan Pediatric Infectious Disease Alliance. We included influenza-related hospitalized patients with age ranging from 6 months to 5 years during the 2012–2013, 2013–2014, 2014–2015, and 2015–2016 influenza seasons. The controls were comparable to cases in age, sex, and residential area and had no influenza-related hospitalization records in the same season. We extracted data from vaccination histories and got the patients’ guardians to complete questionnaires. Data were analyzed using conditional logistic regression. Results: We enrolled 1514 children (421 influenza-infected cases and 1093 controls) in the study. We found seasonal influenza vaccination to be an independent protective factor against hospitalizations owing to influenza [p < 0.01; odds ratio (OR), 0.427; 95% confidence interval (CI), 0.306–0.594]. Children with mean sun exposure time of >7 h/week had a significantly lower risk of influenza-related hospitalizations than those with the mean sun exposure time of ?7 h/week (p < 0.05; OR, 0.667; 95% CI, 0.491–0.906). Conclusions: Seasonal influenza vaccination effectively prevents influenza-related hospitalizations in children aged ?5 years. Besides, >7 h of sun exposure/week may also be associated with lower risk of influenza-related hospitalizations in children. ? 2019 | - |
dc.publisher | Elsevier Ltd | - |
dc.relation.ispartof | Journal of Microbiology, Immunology and Infection | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | influenza vaccine; probiotic agent; influenza vaccine; Article; breast feeding; case control study; child; child hospitalization; controlled study; dietary supplement; drug effect; educational status; female; hospital based case control study; hospital patient; human; infection risk; influenza A; influenza B; influenza vaccination; laboratory; major clinical study; male; mother; newborn care; preschool child; residential area; seasonal influenza; smoking; sun exposure; Taiwan; Taiwanese; time; treatment duration; hospitalization; immunology; infant; influenza; odds ratio; protection; season; statistical model; sunlight; vaccination; Case-Control Studies; Child, Preschool; Female; Hospitalization; Humans; Infant; Influenza Vaccines; Influenza, Human; Logistic Models; Male; Odds Ratio; Protective Factors; Seasons; Sunlight; Taiwan; Vaccination | - |
dc.title | Effects of influenza vaccine and sun exposure time against laboratory-confirmed influenza hospitalizations among young children during the 2012–13 to 2015–16 influenza seasons | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.jmii.2019.09.010 | - |
dc.identifier.pmid | 31732418 | - |
dc.identifier.scopus | 2-s2.0-85075460048 | - |
dc.relation.pages | 880-887 | - |
dc.relation.journalvolume | 52 | - |
dc.relation.journalissue | 6 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Epidemiology and Preventive Medicine | - |
crisitem.author.dept | National Taiwan University Children's Hospital | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.orcid | 0000-0002-9291-260X | - |
crisitem.author.orcid | 0000-0003-2632-1956 | - |
crisitem.author.orcid | 0000-0002-5240-2808 | - |
crisitem.author.orcid | 0000-0002-2567-5501 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
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