https://scholars.lib.ntu.edu.tw/handle/123456789/526092
Title: | Findings of high-resolution chest computed tomography in a young child with Type C Niemann-Pick disease | Authors: | STEVEN SHINN-FORNG PENG Li Y.-W. WUH-LIANG HWU |
Issue Date: | 1998 | Journal Volume: | 10 | Journal Issue: | 4 | Start page/Pages: | 327-331 | Source: | Tzu Chi Medical Journal | Abstract: | Niemann-Pick disease is a rare storage disease involving with deposition of lipids. Manifestations of pulmonary involvement in patients with this disease found using high-resolution computed tomography (HRCT) have been rarely reported in literature. We report findings of high-resolution computed tomography in a 14-month-old child suffering from type C Niemann-Pick disease. The major findings on HRCT of the chest were unevenly thickened dorsal pleura and diffusely thickened interlobular, centrilobular as well as peribronchovascular interstitium. These findings became unremarkable on the follow-up HRCT 6 months after the patient received bone marrow transplantation. Involvement of pulmonary interstitium and pleura in patients with type C Niemann-Pick disease is better demonstrated using HRCT than using chest roentgenogram. Diffuse interstitial involvement in a young child without pulmonary symptoms is suggestive of the possibility of metabolic storage disease. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032406524&partnerID=40&md5=a9898d5eedd8b81abbc5512fb08160f4 https://scholars.lib.ntu.edu.tw/handle/123456789/526092 |
ISSN: | 1016-3190 | SDG/Keyword: | article; bone marrow transplantation; case report; child; computer assisted tomography; female; human; lung interstitium; Niemann Pick disease; pleura; preschool child; thorax radiography |
Appears in Collections: | 醫學系 |
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