https://scholars.lib.ntu.edu.tw/handle/123456789/529280
DC Field | Value | Language |
---|---|---|
dc.contributor.author | SHUENN-NAN CHIU | en_US |
dc.contributor.author | PEI-LAN SHAO | en_US |
dc.contributor.author | Chen H.-C. | en_US |
dc.contributor.author | MING-TAI LIN | en_US |
dc.contributor.author | LI-MIN HUANG | en_US |
dc.contributor.author | Kao F.-Y. | en_US |
dc.contributor.author | Huang S.-K. | en_US |
dc.contributor.author | JOU-KOU WANG | en_US |
dc.contributor.author | MEI-HWAN WU | en_US |
dc.creator | Chiu S.-N.;Shao P.-L.;Chen H.-C.;Ming-Tai Lin;Huang L.-M.;Kao F.-Y.;Huang S.-K.;Wang J.-K.;Wu M.-H. | - |
dc.date.accessioned | 2020-12-21T02:55:03Z | - |
dc.date.available | 2020-12-21T02:55:03Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0022-3476 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955559152&doi=10.1016%2fj.jpeds.2015.12.029&partnerID=40&md5=9e47d9940bfc2695d3c77a9fe544304c | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/529280 | - |
dc.description.abstract | Objective To compare the risk of respiratory syncytial virus (RSV)-associated hospitalization and analyze the epidemiology of RSV infection in patients with cyanotic and acyanotic congenital heart disease (CHD), we analyzed the nationwide health insurance database from 2005-2010. Study design This study included 1050 patients with cyanotic CHD and 7077 patients with acyanotic CHD. Patients with acyanotic CHD were further classified into hemodynamically significant (hs)-acyanotic and non-hs-acyanotic groups according to whether they underwent surgery or took at least 2 anticongestive medications. Results RSV-associated hospitalization was higher in the cyanotic group than in hs-acyanotic and non-hs-acyanotic groups both before 1 year of age (4.8% vs 2.1% vs 1.5%, P <.001) and between 1 and 2 years of age (0.9% vs 0.56% vs 0.14%, P =.003). The hospitalization duration, intensive care, ventilator support prevalence, hospitalization cost, and mortality rate were significantly higher in the cyanotic group than in the other 2 groups. Logistic regression revealed that cyanotic CHD was the most significant risk factor for the ventilator support and RSV-associated mortality. In both patients with cyanotic and acyanotic CHD, RSV-associated hospitalization rate was higher in patients aged younger than 1 year and in spring and autumn in Taiwan, a subtropical country. Conclusions The results show that patients with cyanotic CHD have a higher risk of severe RSV infection than do those with acyanotic CHD. RSV prophylaxis is more important and may reduce costs more for patients with cyanotic CHD. ? 2016 Elsevier Inc. | - |
dc.publisher | Mosby Inc. | - |
dc.relation.ispartof | Journal of Pediatrics | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | acyanotic congenital heart disease; Article; autumn; child; chromosome aberration; comparative study; congenital heart disease; controlled study; cyanotic congenital heart disease; cyanotic heart disease; data base; disease severity; female; health insurance; hospitalization cost; human; ICD-9-CM; infant; infection risk; intensive care; length of stay; major clinical study; male; mortality rate; newborn; prematurity; prevalence; priority journal; respiratory syncytial virus infection; risk factor; sex difference; sex ratio; spring; Taiwan; complication; cyanosis; factual database; Heart Defects, Congenital; hemodynamics; hospitalization; Human respiratory syncytial virus; incidence; register; Respiratory Syncytial Virus Infections; risk; season; antivirus agent; palivizumab; Antiviral Agents; Cyanosis; Databases, Factual; Female; Heart Defects, Congenital; Hemodynamics; Hospitalization; Humans; Incidence; Infant; Infant, Newborn; Insurance, Health; Male; Palivizumab; Registries; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Risk; Seasons; Taiwan | - |
dc.title | Risk of Respiratory Syncytial Virus Infection in Cyanotic Congenital Heart Disease in a Subtropical Area | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.jpeds.2015.12.029 | - |
dc.identifier.pmid | 26822618 | - |
dc.identifier.scopus | 2-s2.0-84955559152 | - |
dc.relation.pages | 25-30 | - |
dc.relation.journalvolume | 171 | - |
item.fulltext | no fulltext | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.openairetype | journal article | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Pediatrics-NTUHHC | - |
crisitem.author.dept | Laboratory Medicine-NTUHHC | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Epidemiology and Preventive Medicine | - |
crisitem.author.dept | National Taiwan University Children's Hospital | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Clinical Pharmacy | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.orcid | 0000-0001-5559-1651 | - |
crisitem.author.orcid | 0000-0003-3334-1330 | - |
crisitem.author.orcid | 0000-0002-1718-7137 | - |
crisitem.author.orcid | 0000-0002-9291-260X | - |
crisitem.author.orcid | 0000-0002-3043-3873 | - |
crisitem.author.orcid | 0000-0002-7074-8087 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
Appears in Collections: | 醫學系 |
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