https://scholars.lib.ntu.edu.tw/handle/123456789/530837
標題: | Factors associated with the prescription of inhaled corticosteroids in GOLD group A and B patients with COPD – Subgroup analysis of the Taiwan obstructive lung disease cohort | 作者: | Wei Y.-F. PING-HUNG KUO Tsai Y.-H. Tao C.-W. Cheng S.-L. Lee C.-H. Wu Y.-K. Chen N.-H. Hsu W.-H. Hsu J.-Y. Lin M.-S. Wang C.-C. |
公開日期: | 2015 | 出版社: | Dove Medical Press Ltd. | 卷: | 10 | 期: | 1 | 起(迄)頁: | 1951-1956 | 來源出版物: | International Journal of COPD | 摘要: | Background and objective: The overprescription of inhaled corticosteroids (ICS) in the current Global Initiative for Chronic Obstructive Lung Disease (GOLD) group A and B patients with chronic obstructive pulmonary disease (COPD) is not uncommon in clinical practice. The aim of this study was to explore the factors associated with the use of ICS in these patients. Methods: The Taiwan obstructive lung disease (TOLD) study was a retrospective, observational nationwide survey of COPD patients conducted at 12 hospitals (n=1,096) in Taiwan. Multivariate logistic regression models were used to explore the predictors of ICS prescription in GOLD group A and B patients. Results: Among the group A (n=179) and group B (n=398) patients, 198 (34.3%) were prescribed ICS (30.2% in group A and 36.2% in group B, respectively). The wheezing phenotype was present in 28.5% of group A and 34.2% of group B patients. Wheezing was the most significant factor for an ICS prescription in group A (odds ratio [OR], 2.33; 95% confidence interval [CI], 1.14-4.75; P=0.020), group B (OR, 1.93; 95% CI, 1.24-2.99; P=0.004), and overall (OR, 2.04; 95% CI, 1.40-2.96; P<0.001). The COPD assessment test score was also associated with an ICS prescription in group B (OR, 1.04; 95% CI, 1.00-1.07; P=0.038). Conclusion: About one-third of the GOLD group A and B patients with COPD in Taiwan are prescribed ICS. Our findings suggest that wheezing and COPD assessment test score are related to the prescription of ICS in these patients. ? 2015 Wei et al. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941889823&doi=10.2147%2fCOPD.S88114&partnerID=40&md5=c01b345a56e6502d94ad102046b778a3 https://scholars.lib.ntu.edu.tw/handle/123456789/530837 |
ISSN: | 1176-9106 | DOI: | 10.2147/COPD.S88114 | SDG/關鍵字: | corticosteroid; bronchodilating agent; corticosteroid; adult; Article; chronic obstructive lung disease; COPD assessment test; drug utilization; female; human; major clinical study; male; observational study; prescription; respiratory tract disease assessment; retrospective study; risk factor; Taiwan; wheezing; abnormal respiratory sound; aged; classification; inhalational drug administration; middle aged; multivariate analysis; odds ratio; pathophysiology; Pulmonary Disease, Chronic Obstructive; severity of illness index; statistical model; very elderly; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Female; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Pulmonary Disease, Chronic Obstructive; Respiratory Sounds; Retrospective Studies; Severity of Illness Index; Taiwan |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。