Successful weaning after plasma exchange for polyneuropathy related to POEMS syndrome
Journal
Journal of Clinical Apheresis
Journal Volume
24
Journal Issue
4
Pages
170-172
Date Issued
2009
Author(s)
Abstract
Respiratory failure due to polyneuropathy associated with POEMS syndrome (Polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) is unusual. In this report, we describe a 47-year-old male patient with polyneuropathy related to POEMS syndrome who suffered from hypercapnic respiratory failure due to progressive weakness of the respiratory muscles. His respiratory muscle strength significantly improved after plasma exchange and was extubated successfully. To our knowledge, this is the first case of POEMS syndrome with aggressive polyneuropathy that was successful treated by plasma exchange and our experience provides insight regarding the optimal management of such patients. ? 2009 Wiley-Liss, Inc.
SDGs
Other Subjects
antibiotic agent; dexamethasone; doxorubicin; vincristine; adrenal insufficiency; adult; anamnesis; antibiotic therapy; article; artificial ventilation; autonomic dysfunction; cancer chemotherapy; case report; cerebrospinal fluid analysis; clinical feature; computer assisted tomography; disease course; dyspnea; endotracheal intubation; evoked somatosensory response; hepatomegaly; human; hypercapnia; hyperpigmentation; hypertrichosis; hypothyroidism; hypoxemia; intensive care unit; limb weakness; male; monoclonal immunoglobulinemia; multiple cycle treatment; nerve conduction disorder; plasmacytoma; plasmapheresis; pleura effusion; pneumonia; POEMS syndrome; polyneuropathy; respiratory failure; thoracocentesis; thorax radiography; tumor recurrence; Humans; Male; Middle Aged; Neural Conduction; Plasma Exchange; POEMS Syndrome; Polyneuropathies
Type
journal article